Results 91 to 100 of about 6,718 (165)

Bacteria-induced uroplakin signaling mediates bladder response to infection.

PLoS Pathogens, 2009
Urinary tract infections are the second most common infectious disease in humans and are predominantly caused by uropathogenic E. coli (UPEC). A majority of UPEC isolates express the type 1 pilus adhesin, FimH, and cell culture and murine studies ...
Praveen Thumbikat, Ruth E Berry, Ge Zhou, Benjamin K Billips, Ryan E Yaggie, Tetiana Zaichuk, Tung-Tien Sun, Anthony J Schaeffer, David J Klumpp   +8 more
doaj   +1 more source

Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets

, 2018
Multivalent carbohydrate–lectin interactions at host–pathogen interfaces play a crucial role in the establishment of infections. Although competitive antagonists that prevent pathogen adhesion are promising antimicrobial drugs, the molecular mechanisms ...
Thomas Luber (6160985), Maier, Timm, Jakob, Roman P., Luber, Thomas, Unverzagt, Carlo, Sauer, Maximilian M., Maximilian M. Sauer (6160982), Maximilian M. Sauer, Timm Maier (1637839), Rudi Glockshuber (658352), Ernst, Beat, Canonica, Fabia, Carlo Unverzagt (749684), Timm Maier, Navarra, Giulio, Thomas Luber, Beat Ernst, Giulio Navarra (1517293), Rudi Glockshuber, Roman P. Jakob, Fabia Canonica, Giulio Navarra, Beat Ernst (1637845), Roman P. Jakob (1637830), Glockshuber, Rudi, Fabia Canonica (6160988), Carlo Unverzagt   +26 more
core   +1 more source

FimH-mediated autoaggregation of Escherichia coli

, 2001
Autoaggregation is a phenomenon thought to contribute to colonization of mammalian hosts by pathogenic bacteria. Type 1 fimbriae are surface organelles of Escherichia coli that mediate D-mannose-sensitive binding to various host surfaces. This binding is
Schembri, Mark, Christiansen, G., Klemm, Per   +2 more
core  

Bacterial colonization, colonic mucosa inflammation and translocation in CEABAC10 mice infected with LF82ΔfimH/fimH_LF82 or LF82ΔfimH/fimH_K12 mutants.

, 2013
(A) Quantification of LF82-ΔfimH/fimHLF82 (black square) or LF82-ΔfimH/fimHK12 (white square) bacteria in the feces of CEABAC10 mice receiving 0.25% DSS in drinking water after oral infection with 109 bacteria on day 0.
Jérémy Denizot (209615), Arlette Darfeuille-Michaud (112082), Margarita Martinez-Medina (277062), Alexander Mellmann (72273), Richard Bonnet (241637), Nicolas Barnich (277067), Nicolas Dreux (277061), Dagmara Kisiela (277064), Evgeni Sokurenko (277065), Sujay Chattopadhyay (158532), Jean-Frédéric Colombel (108372), Christel Neut (241629), Corinne Gower-Rousseau (277066), Maria Billig (277063)   +13 more
core   +1 more source

FimH protein Zonal Phylogeny and MLST tree of AIEC used in this study.

, 2013
(A) Each circle represents a FimH variant coded by phylogenetically distinct fimH allele(s). Circle size reflects the number of strains (from 1 to 12) carrying the corresponding FimH variant.
Jérémy Denizot (209615), Arlette Darfeuille-Michaud (112082), Margarita Martinez-Medina (277062), Alexander Mellmann (72273), Richard Bonnet (241637), Nicolas Barnich (277067), Nicolas Dreux (277061), Dagmara Kisiela (277064), Evgeni Sokurenko (277065), Sujay Chattopadhyay (158532), Jean-Frédéric Colombel (108372), Christel Neut (241629), Corinne Gower-Rousseau (277066), Maria Billig (277063)   +13 more
core   +1 more source

Single nucleotide polypmorphisms of fimH associated with adherence and biofilm formation by serovars of Salmonella enterica

, 2011
Type 1 fimbriae produced by serovars of Salmonella are characterized by their ability to agglutinate guinea pig erythrocytes in the absence of d-mannose but not in its presence.
Dagmara Kisiela, Brett E. Dwyer, Steven Clegg, Karly L. Newton, Evgeni V. Sokurenko   +4 more
core   +1 more source

Evaluation of mammalian codon usage of fimH in DNA vaccine design

Uropathogenic Escherichia coli (UPEC) bacteria are the principal cause of urinary tract infections (UTI). Because these bacteria propagate intracellularly, the cellular immune response is an important factor in UTIs.
Fooladi, Abbas Ali Imani, Mehrabadi, Jalil Fallah, Nourani, Mohammad Reza, Bagherpour, Ghasem, Einollahi, Behzad   +4 more
core   +1 more source

FimH-based display of functional eukaryotic proteins on bacteria surfaces

, 2019
The demand for recombinant proteins for analytic and therapeutic purposes is increasing; however, most currently used bacterial production systems accumulate the recombinant proteins in the intracellular space, which requires denaturating procedures for ...
Chmielewski, Markus, Riet, Nicole, Kuehle, Johannes, Chrobok, Danuta, Hallek, Michael, Abken, Hinrich   +5 more
core   +1 more source

The Genotyping of Iraqi Uropathogenic Escherichia coli with Adhesion Genes FimH and PapGII by Multiplex PCR

Academic Science Journal
Escherichia coli is the most common causative agent of urinary tract infections (UTIs). Important virulence factors are the FimH and PapGII adhesion genes.
Lina Abdulameer Alsaadi, Ghofran Khudhair Ismail   +1 more
doaj   +1 more source

Detection of FimH Gene in Uropathogenic Escherichia coli Strains Isolated From Patients With Urinary Tract Infection [PDF]

, 2015
Background: Urinary tract infections (UTIs) are one of main health problems caused by many microorganisms, including uropathogenic Escherichia coli (UPEC). UPEC strains are the most frequent pathogens responsible for 85% and 50% of community and hospital
Zamanzad, Behnam., Gholipour, Abolfazl., Hojati, Zohreh., Molaie, Razieh., Hashemzadeh-Chaleshtori, Morteza.   +4 more
core