Results 111 to 120 of about 12,591 (290)
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
L'autre de la science. Finitude et altérité chez Althusser
, 2016 This paper aims to show that Althusser's philosophy offers a genuine theoretical framework for thinking the finitude of practices and their relationship to alterity.
Jean Matthys, Matthys, Jean
core +1 more source
O PECADO ORIGINAL NA TEOLOGIA DE ANDRÉS TORRES QUEIRUGA
Último Andar, 2016 Este artigo apresenta um estudo sobre o pecado original na obra Repensar o mal, de Andrés Torres Queiruga. O Teólogo Galego parte da doutrina cristã sobre o pecado original como causa do mal, do sofrimento e da morte enquanto castigo e punição divina ...
Edevilson de Godoy
doaj
Unbearable Birth: Natality in Louise Glück’s Averno
HumanitiesThis essay argues for the importance of the overlooked theme of natality in the poetry of Louise Glück. In its guise as mortality, human finitude causes pain through the permanence of death; in its guise as natality, finitude can also be an occasion for ...
Reena Sastri
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 2014 Cette thèse a l’allure d’une géographie de l’historial visant à cartographier le site où la philosophie atteint sa fin. Une telle géographie obéit à, au moins, deux contraintes matricielles.
Jullien, Stanislas
core
Self and finitude as a transcultural philosophical issue
, 2010 補正完畢國內19990901 ...
狄殷豪; Duessel, Reinhard
core +1 more source