Results 101 to 110 of about 71,417 (302)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Boat of Us: A Concept-Image as an Expression of the Human in the Midst of Reality
RUDN Journal of PhilosophyThe work expresses the current state of the concept of “Us” in light of its latest updates. The Us is clothed in the image of the Boat, which allows us to understand the human in its very material becoming and in the multiplicity of mixtures that ...
Ricardo Espinoza Lolas +1 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
BIOLOGICAL PERSPECTIVES ON FALL AND ORIGINAL SIN
Zygon, 1993 . The paper consists of an argument that goes as follows. Symbols and their elaboration into myths constitute Homo sapiens's most primitive reading of the world and the relation of humans to that world.
doaj +2 more sources
La finitude de l’existence dans l’analytique du Dasein: L’entrelacement du comprendre et de l’affection [PDF]
Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2010 In this paper, I will discuss the Heideggerian interpretation of death in relation with two fundamental structures of the existential analysis: understanding (Verstehen) and state-of-mind (Befindlichkeit).
Cristian Ciocan
doaj
A Thought Experiment with Light: How the ontological form of quantum mechanics is consequent to the principles of relativity theory [PDF]
An imaginative exploration of space and time in which light mediates the relationship between finitude and the Infinite. Light becomes the creative source through which interiority and exteriority are manifested and brought into synchronicity as time ...
Rogers, Timothy M.
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Revista de Pesquisa Cuidado é Fundamental Online, 2010 O objeto dessa investigação são as percepções do graduando de enfermagem acerca do cliente necessitado de suporte tecnológico em processo de morte e morrer.
Paola Rodrigues Costa +1 more
doaj +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Journal of Pastoral Care & Counseling: Advancing theory and professional practice through scholarly and reflective publications, 2019 openaire +2 more sources