Results 51 to 60 of about 71,417 (302)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Revista Filosófica de Coimbra, 2022 Il arrive parfois que la danse rejoigne la philosophie, car l’une et l’autre sont des mouvements et des pensées du corps. Et elles ont en commun de ne se déployer que dans et par la limite. Vivre « aux confins », c’est atteindre les limites et ne jamais
Emmanuel Falque
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
, 2010 Recently Alain Badiou and Quentin Meillassoux have attacked the core of the phenomenological hermeneutic tradition: its commitment to the finitude of human understanding.
Purcell, L. Sebastian
core
, 2018 Enter Object-Oriented Ontology: A New Theory of Everything.Eschewing the verbose and often obscurantist tendencies of other philosopher-authors, Harman tackles what might otherwise be a complicated, controversial and counter-intuitive philosophical ...
Umbrello, Steven
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
IMAGENS DE TEMPO EM BILL VIOLA: INTERPELAÇÕES EXISTENCIAIS DIANTE DO NADA
ARS, 2020 RESUMO Neste artigo, propomos realizar uma análise interpretativa de obras selecionadas do artista norte-americano Bill Viola (n. 1951), visando à caracterização de imagens de tempo que possuam uma dimensão política resistente à rápida obsolescência e ao
Fernanda Albuquerque de Almeida
doaj +1 more source
The Work of Art and Truth of Being as Historical : Reading Being and Time, The Origin of the Work of Art, and the Turn (Kehre) in Heidegger’s Philosophy of the 1930s [PDF]
, 2009 Reading Heidegger’s Being and Time, “The Origin of the Work of Art,” and the 1934-35 lecture courses Hölderlin’s Hymns“Germania” and “The Rhine,” the aim of this essay is twofold. First, the essay attempts to elucidate the manner in which the work of art
Magrini, James
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Why We Should Create Artificial Offspring: Meaning and the Collective Afterlife [PDF]
, 2018 This article argues that the creation of artificial offspring could make our lives more meaningful. By ‘artificial offspring’ I mean beings that we construct, with a mix of human and non-human-like qualities.
Danaher, John
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