Results 101 to 110 of about 20,810 (248)
Bioluminescent Monitoring of NIS-Mediated I Ablative Effects in MCF-7 Xenografts
Molecular Imaging, 2006 Optical imaging has made it possible to monitor response to anticancer therapies in tumor xenografts. The concept of treating breast cancers with 131 I is predicated on the expression of the Na + /I − symporter (NIS) in many tumors and uptake of I in ...
Malavika Ghosh +5 more
doaj +1 more source
Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy. [PDF]
, 2014 Time-lapse fluorescence microscopy is an important tool for measuring in vivo gene dynamics in single cells. However, fluorescent proteins are limited by slow chromophore maturation times and the cellular autofluorescence or phototoxicity that arises ...
Aydin, M +3 more
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Nicotine is the most abundant alkaloid produced by Nicotiana species against insect herbivores. Although it has been known for decades that auxin can strongly inhibit nicotine biosynthesis, the underlying mechanisms have remained unclear.
Miyun Yang +3 more
wiley +1 more source
Molecular Imaging, 2011 Bioluminescence imaging (BLI) of luciferase reporters provides a cost-effective and sensitive means to image biological processes. However, transport of luciferase substrates across the cell membrane does affect BLI readout intensity from intact living ...
Ruimin Huang +3 more
doaj +1 more source
Application of the luciferin-luciferase enzyme system for determination of adenosine triphosphate (ATP) to studies on the mechanisms of herbicide action [PDF]
The luciferin-luciferase enzyme system for determination of ATP is valuable for studies on the mechanisms of herbicide action. Investigations using this system have shown that certain herbicides may act by interfering with ATP production or by blocking ...
St.john, J. B.
core +1 more source
In vivo bioluminescence imaging using orthotopic xenografts towards patient's derived-xenograft Medulloblastoma models [PDF]
, 2017 BACKGROUND: Medulloblastoma is a cerebellar neoplasia of the central nervous system. Four molecular subgrups have been identified (MBWNT, MBSHH, MBgroup3 and MBgroup4) with distinct genetics and clinical outcome.
Asadzadeh, +3 more
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT The regulation of serotonin metabolism during fruit development and ripening remains poorly understood, despite its potential roles in plant defence and human nutrition. Here, we demonstrated that the MADS‐box transcription factor FUL2 acts as a key repressor of serotonin accumulation in tomato by forming a functional module with MADS1. CRISPR‐
Yaping Xu +8 more
wiley +1 more source
Fluorescent Properties of Firefly Luciferases and Their Complexes with Luciferin
Bioscience Reports, 2000 Fluorescence of luciferases from Luciola mingrelica (single tryptophanresidue, Trp-419) and Photinus pyralis (two tryptophan residues, Trp-417,Trp-426) was studied. Analysis of quenching of tryptophan fluorescenceshowed that the tryptophan residue conserved in all luciferases is notaccessible for charged quenchers, which is explained by the presence ...
E I, Dementieva +4 more
openaire +2 more sources
Plant Biotechnology Journal, EarlyView.ABSTRACT Sea Island cotton (Gossypium barbadense) produces premium‐quality fibres, yet the genetic basis underlying its fibre development remains elusive. Here, we identify two key non‐synonymous single nucleotide polymorphisms (SNPs, G/C and G/A) in the gene Gbar_D13G024080, which encodes the TRANSMEMBRANE PROTEIN 209 (TMEM209). These SNPs resulted in
Kaiyun Jiang +25 more
wiley +1 more source