Results 101 to 110 of about 14,327 (227)

Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals

BioTechniques, 2007
A relatively new strategy to longitudinally monitor tumor load in intact animals and the effects of therapy is noninvasive bioluminescence imaging (BLI).
Clara P.W. Klerk, Renée M. Overmeer, Tatjana M.H. Niers, Henri H. Versteeg, Dick J. Richel, Tessa Buckle, Cornelis J.F. Van Noorden, Olaf van Tellingen   +7 more
doaj   +1 more source

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

Advanced Science, Volume 13, Issue 37, 3 July 2026.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang, Zijin Liu, Minshan Jin, Junting Liu, Shihao Wei, Dengmao Yang, Saiqi Yang, Yuan Guo, Mingxun Chen   +8 more
wiley   +1 more source

Fast and Sensitive Swab-Based Bioluminescent Detection Method for Meat and Chicken Microbiological Contamination Using Amydetes vivianii Firefly Luciferase

Chemosensors
New faster and more sensitive detection methods are required for food microbiological contamination quality control throughout the entire handling process.
Alessandra Freitas Serain, Daniel Rangel de Souza, Vadim R. Viviani   +2 more
doaj   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, Volume 13, Issue 37, 3 July 2026.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Engineering Bone‐Targeted LNP Delivery of Anti‐Sclerostin Antibody mRNA for the Treatment of Osteoporosis

Journal of Biomedical Materials Research Part A, Volume 114, Issue 7, July 2026.
ABSTRACT Messenger RNA (mRNA) therapy represents a transformative platform in regenerative medicine, but its application to skeletal disorders remains limited by the pronounced hepatic tropism of conventional lipid nanoparticle (LNP) delivery systems.
Pengcheng Ren, Diaodiao Wang, Wenqiang Sun, Danning Li, Sidong Yang, Shudong Zhang, Yiquan Zhang, Yubo Liu, Peng Hu, Jiaxin Li, Qi Yao   +10 more
wiley   +1 more source

Experimental and Theoretical Study for Core Excitation of Firefly Luciferin in Carbon K‑Edge Spectra

Carbon (C) K-edge X-ray absorption spectra for firefly luciferin were measured and assigned using time-dependent density functional theoretical calculations for luciferin anion and dianion to elucidate the effect of hydroxy-group deprotonation.
Yoshifumi Noguchi (1619881), Yuto Kudo (17797192), Nobuaki Koga (1502419), Hideyuki Itabashi (1645801), Jun-ichi Adachi (17797195), Masanari Nagasaka (1362405), Miyabi Hiyama (1619878), Fumitoshi Kumaki (9528071)   +7 more
core   +1 more source

Rapid Bioluminescent Antibiotic Susceptibility Assay

Антибиотики и Химиотерапия, 2020
Rapid testing of pathogen susceptibility to antibiotics is of great practical value for rational chemotherapy of pyoinflammatory deseases and postoperative complications of microbial etiology. The standard microbiological methods i.e.
V. G. Frundzhyan, N. N. Ugarova, L. A. Blatun, R. P. Terekhova, E. V. Rusanova   +4 more
doaj  

Bioluminescent Monitoring of NIS-Mediated I Ablative Effects in MCF-7 Xenografts

Molecular Imaging, 2006
Optical imaging has made it possible to monitor response to anticancer therapies in tumor xenografts. The concept of treating breast cancers with 131 I is predicated on the expression of the Na + /I − symporter (NIS) in many tumors and uptake of I in ...
Malavika Ghosh, Sanjiv Sam Gambhir, Abhijit De, Kent Nowels, Michael Goris, Irene Wapnir   +5 more
doaj   +1 more source

Constitution and function of intergenic genome regions in cultivated versus annual wild soybean in China

Journal of Integrative Plant Biology, Volume 68, Issue 7, Page 2105-2127, July 2026.
Three‐case restricted two‐stage multi‐locus multi‐allele genome‐wide association study identified main‐effect genes and detected the regulatory effects of intergenic loci on genes, enabling comprehensive dissection of the genic‐intergenic genetic system for quantitative traits and providing a strategy for studying their genetic basis.
Xiaoshuai Hao, Xinyang Hu, Yongpeng Pan, Qi Zhang, Ran Ou, Fenfen Jiang, Fangdong Liu, Jiaoping Zhang, Wubin Wang, Guangnan Xing, Junyi Gai, Jianbo He   +11 more
wiley   +1 more source

Incorporation of 1,4-hydroquinone and ¹³C-labeled L-cysteines into firefly luciferin in an adult lantern of L. lateralis.

, 2013
A. Predicted firefly luciferins incorporated from 1,4-hydroquinone and L-Cys[U-13C3]. B. Predicted firefly luciferins incorporated from 1,4-hydroquinone and L-Cys[1-13C3]. C.
Naoki Yoshida (504407), Shusei Kanie (504408), Makoto Ojika (504409), Satoshi Inouye (203922), Yuichi Oba (504406)   +4 more
core   +1 more source