Results 131 to 140 of about 394,837 (342)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Mountain bananas from the french west indies [PDF]
Banana production is a key economic resource in the French West Indies. It is essential that growers in this region enhance their sales by proposing new products-such as mountain bananas-in response to high market competition from other exporting regions
Brat, Pierre +2 more
core
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Beurteilung der Fruchtqualität beim Apfel im Rahmen des EU-Projekts Hidras [PDF]
The EU project Hidras (High Quality Disease Resistant Apples for a sustainable agriculture, QLK5-CT-2002-01-01492) aims to identify genetic factors controlling apple fruit quality with the objective of increasing the acceptability of disease resistant ...
Eigenmann, Christian, Kellerhals, Markus
core
Emotion Suppression and Firm Disclosures
Kristina M. Rennekamp +2 more
openalex +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Entry into the Crypto Assets Business by Global Financial Services Firms
Soon Yeong Choi
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Suitability of peach and nectarine cultivars for organic production under pannonic climate conditions in Austria [PDF]
The suitability of nectarine and peach cultivars for organic production was examined in a field experiment in the experimental orchard of the institute in Vienna. Therefore, fifteen cultivars including Redhaven as standard cultivar were planted in 2003
Keppel, H. +2 more
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source

