Results 71 to 80 of about 830,683 (322)
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Model-based versus model-free feeding control and water quality monitoring for fish growth tracking in aquaculture systems [PDF]
arXiv, 2023 The high concentration level of the environmental factors, such as a high ammonia concentration and pH level, affect the water quality, affecting fish's survival and mass death. Therefore, there is a critical need to develop control strategies to determine optimal, efficient, and reliable feeding and water quality monitoring processes.
arxiv
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
New univariate characterization of fish community size structure improves precision beyond the Large Fish Indicator [PDF]
arXiv, 2017 The size structure of fish-communities is an emergent high-level property of marine food webs responsive to changes in structure and function. To measure this food web property using data arising from routine fisheries surveys, a simple metric known as Typical Length has been proposed as more suitable than the Large Fish Indicator, which has been ...
arxiv
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Counting Fish and Dolphins in Sonar Images Using Deep Learning [PDF]
arXiv, 2020 Deep learning provides the opportunity to improve upon conflicting reports considering the relationship between the Amazon river's fish and dolphin abundance and reduced canopy cover as a result of deforestation. Current methods of fish and dolphin abundance estimates are performed by on-site sampling using visual and capture/release strategies.
arxiv
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Incremental events in the construction of sambaquis, southeastern Santa Catarina.
Revista do Museu de Arqueologia e Etnologia, 2000 Moundbuilding is a cross-cultural phenomenon of nearly world-wide scope. In this article some of the moundbuilding processes related to the sambaquis (shellmounds) from the coast of Santa Catarina State, Brasil, are examined, focusing on field research ...
Suzanne K. Fish +3 more
doaj +1 more source
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source