Results 71 to 80 of about 3,056,976 (349)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Incremental events in the construction of sambaquis, southeastern Santa Catarina.

open access: yesRevista do Museu de Arqueologia e Etnologia, 2000
Moundbuilding is a cross-cultural phenomenon of nearly world-wide scope. In this article some of the moundbuilding processes related to the sambaquis (shellmounds) from the coast of Santa Catarina State, Brasil, are examined, focusing on field research ...
Suzanne K. Fish   +3 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nuclear DNA content variation within four species of Asian catfish of family Pangasidae and their two interspecific hybrids by flow cytometry

open access: yesJurnal Akuakultur Indonesia, 2020
 Nuclear DNA content (NDC) of species or population is believed to have been formed naturally by many mechanisms such chromosomal mutation, insertion and deletion, transposable element, and duplication.
Imron   +3 more
doaj   +1 more source

Ballistic limit of 6061 T6 aluminum and threat to surface coatings for use with orbiting space station space suit materials [PDF]

open access: yes
In recent years orbiting satellites, spent components, collisions and explosions have populated the near earth orbit with debris potentially more hazardous than the average meteoroid debris.
Fish, D.
core   +1 more source

Effects of fish-meal, cow blood-meal, and sorghum diets on food utilization and growth of cage cultured Sarotherodon niloticus [PDF]

open access: yes, 1986
The growth responses and feed utilization of Sarotherodon niloticus held in metal cages in a pond and fed diets containing fish-meal, cow blood-meal or sorghum was studied.
Ufodike, E.B.C., Ugwuzor, G.N.
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Assessing detection of New Zealand mudsnails at low densities in Arizona streams [PDF]

open access: yesAquatic Invasions
The New Zealand mudsnail (NZMS) is a small-bodied gastropod that has successfully invaded waters across multiple continents. This species has the ability to reach extremely high densities in streams and exclude other aquatic macroinvertebrates which ...
Crosby K. Hedden   +4 more
doaj   +3 more sources

TRIVALENT CHROMIUM (CR+3) IN DIETARY CARBOHYDRATE AND ITS EFFECT ON THE GROWTH OF COMMONLY CULTIVATED FISH [PDF]

open access: yes, 2016
Trivalent chromium (Cr+3) is an essential trace mineral for fish bio-physiological functions. Researches on Cr+3 in the form of organic compound indicated that the mineral affected the bio-activity of insulin, the blood glucose influx, and subsequently ...
Hastuti, Sri, Subandiyono, Subandiyono
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy