Results 81 to 90 of about 591,916 (369)

Genetic alterations and cancer formation in a European flatfish at sites of different contamination burdens [PDF]

, 2014
Fish diseases are an indicator for marine ecosystem health since they provide a biological end-point of historical exposure to stressors. Liver cancer has been used to monitor the effects of exposure to anthropogenic pollution in flatfish for many years.
Bignell, John P., Derocles, Stephane A. P., Derocles, Stéphane A P, Derocles, Stéphane A. P., Lerebours, Adelaide, Lerebours, Adélaïde, Lyons, Brett P., Rotchell, Jeanette, Rotchell, Jeanette M., Stentiford, Grant, Stentiford, Grant D.   +10 more
core   +2 more sources

Environmental fate of the anti-parasitic ivermectin in an aquatic micro-ecological system after a single oral administration [PDF]

PeerJ, 2019
Background Ivermectin (IVM) has been widely used in the aquaculture industry since its efficacy against parasites. However, the degradation of IVM was very slow in aquatic environments and the environmental fate of IVM in a complete aquatic system was ...
Di Wang, Bing Han, Shaowu Li, Yongsheng Cao, Xue Du, Tongyan Lu   +5 more
doaj   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Expression signatures of cisplatin- and trametinib-treated early-stage medaka melanomas [PDF]

, 2019
Small aquarium fish models provide useful systems not only for a better understanding of the molecular basis of many human diseases, but also for first-line screening to identify new drug candidates.
Boswell, William, Klotz, Barbara, Kneitz, Susanne, Lu, Yuan, Postlethwait, John, Shartl, Manfred, Walter, Ronald B, Warren, Wesley   +7 more
core   +2 more sources

In Silico Characterization of Resistance and Virulence Genes in Aeromonas jandaei Strains Isolated from Oreochromis niloticus in Brazil

Microorganisms
Understanding the genetic characteristics of Aeromonas jandaei in Brazilian aquaculture is crucial for developing effective control strategies against this fish pathogen. The present study conducted a genomic analysis of Brazilian A. jandaei strains with
Marcela Laryssa Oliveira Duarte, Diego Lucas Neres Rodrigues, Gabryel Bernardo Vieira de Lima, Juan Carlos Ariute, Gisele Veneroni Gouveia, João José de Simoni Gouveia, Vasco Azevedo, Bertram Brenig, Eric Guédon, Guilherme Campos Tavares, Mateus Matiuzzi da Costa, Ulisses de Pádua Pereira, Flávia Figueira Aburjaile   +12 more
doaj   +1 more source

Characteristics of selected bioaccumulative substances and their impact on fish health

Journal of Veterinary Research, 2016
The aim of this article was to evaluate the influence and effects of chosen bioaccumulative substances i.e. heavy metals, pesticides, and polychlorinated biphenyls (PCBs) on fish, as well as provide information on time trends and potential threat to ...
Walczak Marek, Reichert Michał
doaj   +1 more source

Divergent Evolution of Progesterone and Mineralocorticoid Receptors in Terrestrial Vertebrates and Fish Influences Endocrine Disruption [PDF]

arXiv, 2021
There is much concern about disruption of endocrine physiology regulated by steroid hormones in humans, other terrestrial vertebrates and fish by industrial chemicals, such as bisphenol A, and pesticides, such as DDT. These endocrine-disrupting chemicals influence steroid-mediated physiology in humans and other vertebrates by competing with steroids ...
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Skeletal malformations among the Clarias species from fish mongers in Ekiti State [PDF]

, 2011
Clarias species purchased from fish mongers from Ado – Ekiti, Ikun Ekiti, Itapaji – Ekiti Nigeria were examined for possible deformities in any part of their body.
Fagbuaro , Omotayo, Oso, James Abayomi
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source