Results 221 to 230 of about 2,532,132 (302)

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Krill oil increases plasma omega-3 fatty acids more than fish oil in healthy adults: a double-blind randomized controlled trial. [PDF]

Am J Clin Nutr
Loukil I, Vachon A, Çaku A, Plourde M.
europepmc   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

Advanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang, Huadong Xing, Antonella Di Pizio, Qinfei Ke, Xingran Kou, Dachuan Zhang   +5 more
wiley   +1 more source

Encapsulation of Fish Oil in Pullulan/Sodium Caseinate Nanofibers: Fabrication, Characterization, and Oxidative Stability. [PDF]

Foods
Dabora S, Jiang B, Hlaing KSS.
europepmc   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Replacement of Supplemental Fish Oil by Linseed or Soybean Oil Reshapes Hepatic Lipid Metabolism Without Compromising Growth in Juvenile Chinese Soft-Shelled Turtle (<i>Pelodiscus sinensis</i>). [PDF]

Animals (Basel)
Li R, Guo Y, Zhao E, Ge C, Sun J.
europepmc   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Synergistic effects of <i>Piper ornatum</i> and lemuru fish oil on <i>in vitro</i> rumen fermentation, nutrient digestibility, and methane mitigation. [PDF]

Vet World
Zain M, Despal D, Tanuwiria UH, Yunilas Y, Pazla R, Putri EM, Yanti G, Ikhlas Z, Sari RR, Sucitra LS, Utami BV.   +10 more
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Differential Effects of DHA-Rich Fish Oil Supplementation on Intestinal and Pulmonary Alterations in Experimental Malaria Caused by <i>Plasmodium berghei</i> NK65. [PDF]

ACS Omega
Pereira LPMC, Silva-Rodrigues JH, Pinheiro FM, Machado LF, da Silva ACF, Marques CB, Gomes MT, Gonçalves FMM, Bezerra-Bellei JC, Brum G, Dias VC, Hipólito JR, Bastos AN, Nascimento HLDS, E Silva FMC, D'Avila H, Neto AF, Reis Junior JL, Rocha VN, Ribeiro-Gomes FL, Castro JMA, Scopel KKG.   +21 more
europepmc   +1 more source