A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source
Monogeneans are the parasites mostly found on the body surface and gills of fish and can cause large losses in farmed fish. Some studies demonstrate elevated parasitic levels causing hematological alterations.
GT Jerônimo +6 more
doaj +1 more source
A survey of coccidian infection (Apicomplexa: Eimeriidaea) of freshwater fish in South Africa [PDF]
Fish coccidia, especially Goussia and Eimeria spp., are common and frequent parasites of fish. The majority of the known species has been described from the Eurasian continent.
Avenant-Oldewage, Annemarie +2 more
core
CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura +4 more
wiley +1 more source
Fauna of fish parasites in water bodies of the north‑east of Armenia
Background. Fish parasitic diseases seriously damage fish farming, and significantly influence the fish viability. North-East region of Armenia (Sevan lake basin, and Aghstev river valley) are the most important recreation center of the country ...
Ruzanna L. Hovhannisyan +4 more
doaj +1 more source
Synopsis of the parasites in Iranian freshwater fishes [PDF]
Two hundred forty-seven species of parasites from Iranian freshwater fishes are presented in this synopsis. The parasites were recorded from infestations in fish from different parts of the country and summarized according to host species, organs were ...
Masoumian, M., Pazooki, J.
core
Hatching Strategies in Monogenean (Platyhelminth) Parasites that Facilitate Host Infection [PDF]
In parasites, environmental cues may influence hatching of eggs and enhance the success of infections. The two major endoparasitic groups of parasitic platyhelminths, cestodes (tapeworms) and digeneans (flukes), typically have high fecundity, infect more
Armstrong +13 more
core +1 more source
Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Seasonal dietary shifts enhance parasite transmission to lake salmonids during ice cover
Changes in abiotic and biotic factors between seasons in subarctic lake systems are often profound, potentially affecting the community structure and population dynamics of parasites over the annual cycle.
Sebastian Prati +3 more
doaj +1 more source
Pathology associated with larval Eustrongylides sp. (Nematoda: Dioctophymatoidea) infection in Galaxias maculatus (Actinopterygii: Galaxiidae) from Patagonia, Argentina [PDF]
Helminth infections within tissues tend to be subjected to a host response that can include encapsulation and melanization to isolate the parasite. The effectiveness of this response depends on the host species. During a survey of parasites of the native
Brugni, Norma Leonor +2 more
core +1 more source

