Results 51 to 60 of about 451,388 (309)

Inverse relationship between genetic diversity and epigenetic complexity [PDF]

, 2008
Early studies of molecular evolution revealed a correlation between genetic distance and time of species divergence. This observation provoked the molecular clock hypothesis and in turn the ‘Neutral Theory’, which however remains an ...
Shi Huang
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

An overview of the utilisation of microalgae biomass derived from nutrient recycling of wet market wastewater and slaughterhouse wastewater

International Aquatic Research, 2017
Microalgae have high nutritional values for aquatic organisms compared to fish meal, because microalgae cells are rich in proteins, lipids, and carbohydrates. However, the high cost for the commercial production of microalgae biomass using fresh water or
A. Y. Maizatul, Radin Maya Saphira Radin Mohamed, Adel A. Al-Gheethi, M. K. Amir Hashim   +3 more
doaj   +1 more source

First paleoproteome study of fossil fish otoliths and the pristine preservation of the biomineral crystal host

Scientific Reports, 2023
Otoliths are calcium carbonate components of the stato-acoustical organ responsible for hearing and maintenance of the body balance in teleost fish. During their formation, control over, e.g., morphology and carbonate polymorph is influenced by complex ...
Jarosław Stolarski, Jeana Drake, Ismael Coronado, Ana R. Vieira, Urszula Radwańska, Elizabeth A. C. Heath-Heckman, Maciej Mazur, Jinming Guo, Anders Meibom   +8 more
doaj   +1 more source

Intracellular interferons in fish : a unique means to combat viral infection [PDF]

, 2013
Peer reviewedPublisher ...
A Lopez-Munoz, A Matsuo, A Pindel, AJ Sadler, B Sun, Bei Huang, Bertrand Collet, C Stein, Chris J. Secombes, CM Ahmed, D Aggad, E Kalie, EL Ooi, F Sun, FF Yu, J Zou, J Zou, J Zou, J Zou, JM Gonzalez-Navajas, Jun Zou, Karen L. Mossman, KE Taylor, M Chang, M Shin-Ya, Ming-Xian Chang, MK Purcell, N Sathish, O Haller, OJ Hamming, PE Phelan, Pin Nie, S Biacchesi, S Campbell, S Long, S Long, SA Martin, SV Kotenko, SY Liu, T Svingerud, V Bergan, Y Palti, YB Zhang, Z Li, Z Qi, Zhanglong Yu   +45 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Alternative Proteins for Fish Diets: Implications beyond Growth

Animals, 2022
Aquaculture has been challenged to find alternative ingredients to develop innovative feed formulations that foster a sustainable future growth. Given the most recent trends in fish feed formulation on the use of alternative protein sources to decrease ...
Cláudia Aragão, Ana Teresa Gonçalves, Benjamín Costas, Rita Azeredo, Maria João Xavier, Sofia Engrola   +5 more
doaj   +1 more source

Recombinant DnaK orally administered protects axenic European sea bass against vibriosis [PDF]

, 2020
Vibrio anguillarum causes high mortality in European sea bass (Dicentrarchus labrax) larviculture and is a hindering factor for successful sustainable aquaculture of this commercially valuable species.
Bajek, Aline, Bossier, Peter, De Geest, Bruno, Dierckens, Kristof, Norouzitallab, Parisa, Vanrompay, Daisy, Yaacob, Eamy Nursaliza   +6 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source