Results 111 to 120 of about 390,765 (354)
Human Dimensions of Marine Fisheries: Using GIS to Illustrate Land-Sea Connections in the Northeast U.S. Herring, Clupea harengus, Fishery [PDF]
, 2005 Geographic Information Systems can help improve ocean literacy and inform our understanding of the human dimensions of marine resource use. This paper describes a pilot project where GIS is used to illustrate the connections between fish stocks and the ...
Da Silva, Patricia Pinto +1 more
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Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
West Coast Groundfish in California Value Chain Assessment [PDF]
, 2015 The West Coast Groundfish fishery is one of the most complex U.S. fisheries to ever successfully end overfishing and rebuild its depleted stocks. This resulted in the certification of 13 species by the Marine Stewardship Council in 2014.
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Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Alternative Management Regimes for multiple species fisheries [PDF]
This empirical study examines welfare gains and losses that would result from alternative fishery management regimes. In an application to the North Sea demersal fisheries, the study shows that these fishery resources can give rise to large economic rent.
Kim, Chungsoo
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Robust Management, Risk and the Ecosystem Approach to Fisheries [PDF]
, 2008 Biodiversity has not been a prominent consideration in conventional fishery management, even though biological concerns and the concept of "sustainability" are long-established in fisheries. This is because traditionally, the focus of management has been
Anthony Charles
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Multi-output distance function for the North Sea Beam Trawl Fishery [PDF]
, 2002 Interactions between species in a fishery may be either biological (e.g. predatorprey) or technical (e.g. joint production). Technical interactions within fisheries have generally been assumed to exist, although the strength of these interactions has ...
Bjorndal, T., Koundouri, P., Pascoe, S.
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Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source