Results 91 to 100 of about 83,026 (211)

Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION. [PDF]

, 2016
The relevance of mitochondrial phosphate carrier (PiC), encoded by SLC25A3, in bioenergetics is well accepted. However, little is known about the mechanisms mediating the cellular impairments induced by pathological SLC25A3 variants.
Acoba, Michelle G., Anderson-Pullinger, Lauren, Claypool, Steven M., Golenár, Tünde, Gál, Aniko, Hajnóczky, György, Li, Qipei, Moffat, Cynthia, Seifert, Erin L., Sondheimer, Neal   +9 more
core   +2 more sources

NUDIX hydrolases target specific inositol pyrophosphates and regulate phosphate homeostasis and bacterial pathogen susceptibility in Arabidopsis

Journal of Integrative Plant Biology, EarlyView.
NUDIX‐type hydrolase enzymes of subclade I and II preferentially target the inositol pyrophosphate messengers 4‐ and 3‐InsP7, respectively. Inactivation of subclade II NUDTs disrupts phosphate homeostasis and enhances bacterial resistance, revealing connections between defense and nutrient signaling.
Robin Schneider, Klea Lami, Isabel Prucker, Sara Christina Stolze, Annett Strauß, Julie Marie Schmidt, Simon M. Bartsch, Kevin Langenbach, Esther Lange, Kevin Ritter, David Furkert, Natalie Faiß, Sandeep Kumar, M. Shamim Hasan, Athanasios Makris, Lukas Krusenbaum, Stefanie Wege, Yemisrach Zewdu Belay, Simon Kriescher, Jeremy The, Michael Harings, Florian M. W. Grundler, Martina K. Ried‐Lasi, Heiko Schoof, Philipp Gaugler, Marília Kamleitner, Dorothea Fiedler, Hirofumi Nakagami, Ricardo F. H. Giehl, Thomas Lahaye, Saikat Bhattacharjee, Henning J. Jessen, Verena Gaugler, Gabriel Schaaf   +33 more
wiley   +1 more source

Global transcriptional response after exposure of fission yeast cells to ultraviolet light

BMC Cell Biology, 2009
Background In many cell types, including the fission yeast Schizosaccharomyces pombe, a set of checkpoints are induced by perturbations of the cell cycle or by DNA damage.
Grallert Beáta, Nilsen Hilde, Fensgård Øyvind, Skjølberg Henriette C, Boye Erik   +4 more
doaj   +1 more source

Anaphase B. [PDF]

, 2016
Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid, Civelekoglu-Scholey, Gul, Scholey, Jonathan M   +2 more
core   +2 more sources

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Bifurcation analysis of a model of the budding yeast cell cycle

, 2004
We study the bifurcations of a set of nine nonlinear ordinary differential equations that describe the regulation of the cyclin-dependent kinase that triggers DNA synthesis and mitosis in the budding yeast, Saccharomyces cerevisiae.
Battogtokh, Dorjsuren, Tyson, John J.
core   +1 more source

ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release. [PDF]

, 2017
The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol.
Koehler, Carla M, Steffen, Janos
core   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Essential developmental processes in Physcomitrium patens require distinct levels of total activity provided by functionally redundant PpROP GTPases

New Phytologist, Volume 248, Issue 6, Page 2865-2890, December 2025.
Summary RHO (RAS homologous) GTPases regulate important cellular and developmental processes in most eukaryotes. Plant‐specific ROP (RHO of plants) GTPase families expanded and functionally diversified during the evolution of vascular plants, but contain few members in nonvascular extant relatives of early land plants.
Aude Le Bail, Benedikt Kost, Janina Nüssel, Tamara Isabeau Lolis, David Koch, Hildegard Voll, Sylwia Schulmeister, Alexander Kaier, Karin Ljung, Maria Ntefidou   +9 more
wiley   +1 more source

Role for the fission yeast RecQ helicase in DNA repair in G2. [PDF]

, 2003
Members of the RecQ helicase subfamily are mutated in several human genomic instability syndromes, such as Bloom, Werner, and Rothmund-Thomson syndromes. We show that Rqh1, the single Schizosaccharomyces pombe homologue, is a 3'-to-5' helicase and exists
Ampatzidou, Eleni, Andersen, Anni H, Laursen, Louise V, Murray, Johanne M   +3 more
core   +3 more sources