Results 91 to 100 of about 562,079 (281)

Multi-Layered Regulations on the Chromatin Architectures: Establishing the Tight and Specific Responses of Fission Yeast fbp1 Gene Transcription

Biomolecules, 2022
Transcriptional regulation is pivotal for all living organisms and is required for adequate response to environmental fluctuations and intercellular signaling molecules.
Ryuta Asada, Kouji Hirota
doaj   +1 more source

Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast

Nature Communications, 2014
Most long non-coding RNAs (lncRNAs) encoded by eukaryotic genomes remain uncharacterized. Here we focus on a set of intergenic lncRNAs in fission yeast. Deleting one of these lncRNAs exhibited a clear phenotype: drug sensitivity. Detailed analyses of the
Ryan Ard, Pin Tong, R. Allshire
semanticscholar   +1 more source

Spd2 assists Spd1 in modulation of RNR architecture but does not regulate deoxynucleotide pools [PDF]

, 2014
In yeasts, small intrinsically disordered proteins (IDPs) modulate ribonucleotide reductase (RNR) activity to ensure an optimal supply of dNTPs for DNA synthesis. The S. pombe Spd1 protein can directly inhibit the large RNR subunit (R1), import the small
Basrai, Beck, Bester, Bähler, Chabes, Danielsson, Elledge, Fairman, Fleck, Halazonetis, Hofer, Holmberg, Holmberg, Håkansson, Kjaerulff, Knutsen, Lee, Liu, Liu, Marguerat, Maundrell, Moreno, Moss, Nestoras, Nielsen, Nordlund, Reichard, Rhind, Salguero, Tompa, Uchiki, Weinberg, Woollard, Wu, Yoshida, Zhao, Zhao, Zolezzi   +37 more
core   +1 more source

Exploring Genetic Interactions with Telomere Protection Gene pot1 in Fission Yeast

Biomolecules, 2023
The regulation of telomere length has a significant impact on cancer risk and aging in humans. Circular chromosomes are found in humans and are often unstable during mitosis, resulting in genome instability.
Masaru Ueno
doaj   +1 more source

Cytokinetic nodes in fission yeast arise from two distinct types of nodes that merge during interphase

Journal of Cell Biology, 2014
Two distinct classes of cortical nodes form separately during interphase in fission yeast cells and then merge at the cell equator by a diffuse-and-capture mechanism to prepare nodes to form the contractile ring for cytokinesis.
Matthew Akamatsu, J. Berro, K. Pu, I. Tebbs, T. Pollard   +4 more
semanticscholar   +1 more source

Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast

eLife, 2014
Hybrid sterility is one of the earliest postzygotic isolating mechanisms to evolve between two recently diverged species. Here we identify causes underlying hybrid infertility of two recently diverged fission yeast species Schizosaccharomyces pombe and S.
Sarah E. Zanders, Michael T. Eickbush, Jonathan S Yu, Ji-Won Kang, Kyle R Fowler, Gerald R. Smith, Harmit S. Malik   +6 more
semanticscholar   +1 more source

Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases [PDF]

, 2009
Neurons are metabolically active cells with high energy demands at locations distant from the cell body. As a result, these cells are particularly dependent on mitochondrial function, as reflected by the observation that diseases of mitochondrial ...
Alexander, Baloyannis, Banchs, Bossy-Wetzel, Brockmann, Cassidy-Stone, Chang, Chen, Cho, Clark, D. C. Chan, de Brito, Delettre, Dodson, Exner, Fransson, Frezza, Gispert, H. Chen, Hollenbeck, Kim, Kim, Li, Liot, Lustbader, Macaskill, Meeusen, Milone, Mortiboys, Okamoto, Orr, Park, Parone, Popp, Reis, Suen, Ten Dijke, Trushina, Wang, Waterham, Wood-Kaczmar, Zuchner, Z  chner   +42 more
core   +3 more sources

lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast

Genes & Development, 2014
Vasiljeva and colleagues identify a mechanism regulating transcriptional repression of pho1, which encodes a major secreted acid phosphatase required for extracellular phosphate uptake in fission yeast.
Sneha Shah, Sina Wittmann, Cornelia Kilchert, L. Vasiljeva   +3 more
semanticscholar   +1 more source

A new pma1 mutation identified in a chronologically long-lived fission yeast mutant

FEBS Open Bio, 2014
We isolated a chronologically long-lived mutant of Schizosaccharomyces pombe and found a new mutation in pma1+ that encoded for an essential P-type proton ATPase.
Chikako Naito, Hirokazu Ito, Tomoko Oshiro, Hokuto Ohtsuka, Hiroshi Murakami, Hirofumi Aiba   +5 more
doaj   +1 more source

The novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis

Journal of Cell Biology, 2014
In fission yeast, Rng8 and Rng9 form oligomers and cluster multiple Myo51 dimers to regulate Myo51 localization and function during cytokinesis.
Ning Wang, Libera Lo Presti, Yi-Hua Zhu, Minhee Kang, Zhengrong Wu, Sophie G. Martin, Jian-Qiu Wu   +6 more
semanticscholar   +1 more source