Results 91 to 100 of about 84,111 (254)

Multi-Layered Regulations on the Chromatin Architectures: Establishing the Tight and Specific Responses of Fission Yeast fbp1 Gene Transcription

Biomolecules, 2022
Transcriptional regulation is pivotal for all living organisms and is required for adequate response to environmental fluctuations and intercellular signaling molecules.
Ryuta Asada, Kouji Hirota
doaj   +1 more source

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

VIEW, EarlyView.
Figure.1 Schematic diagram of MS‐based mitochondrial proteomics for cancer biomarker discovery. The workflow highlights the integration of advanced technological platforms in mitochondrial proteomics and their application in cancer biomarker discovery.
Zheng Cao, ZiKun Song, Weijie Zhou, Xiaohui Liu, Yanling Liu, Peng R. Chen, Kun Qian   +6 more
wiley   +1 more source

Microscopy of Fission Yeast Sexual Lifecycle [PDF]

Journal of Visualized Experiments, 2016
The fission yeast Schizosaccharomyces pombe has been an invaluable model system in studying the regulation of the mitotic cell cycle progression, the mechanics of cell division and cell polarity. Furthermore, classical experiments on its sexual reproduction have yielded results pivotal to current understanding of DNA recombination and meiosis.
Vjestica, Aleksandar, Merlini, Laura, Dudin, Omaya, Bendezu, Felipe O., Martin, Sophie   +4 more
openaire   +2 more sources

Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage [PDF]

, 1994
The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction.
Al-Harithy, R, Carr, A M, Lehmann, A R, Murray, J M, Sheldrick, K S, Tavassoli, M, Watts, F Z   +6 more
core   +1 more source

Bayesian meta-analysis for identifying periodically expressed genes in fission yeast cell cycle

, 2010
The effort to identify genes with periodic expression during the cell cycle from genome-wide microarray time series data has been ongoing for a decade. However, the lack of rigorous modeling of periodic expression as well as the lack of a comprehensive ...
Fan, Xiaodan, Liu, Jun S., Pyne, Saumyadipta   +2 more
core   +1 more source

Synthetic biology approaches to generate temperature‐sensitive alleles for the Sterile Insect Technique

Insect Science, EarlyView.
Abstract The Sterile Insect Technique (SIT) is an environmentally friendly, sustainable pest control approach, which uses large‐scale releases of sterile insects to suppress or eradicate target populations through infertile matings. The efficiency of SIT is enhanced by male‐only releases requiring genetic sexing strains (GSSs) that are classically ...
Chun Yin Leung, Ernst A. Wimmer, Hassan M. M. Ahmed   +2 more
wiley   +1 more source

A new pma1 mutation identified in a chronologically long-lived fission yeast mutant

FEBS Open Bio, 2014
We isolated a chronologically long-lived mutant of Schizosaccharomyces pombe and found a new mutation in pma1+ that encoded for an essential P-type proton ATPase.
Chikako Naito, Hirokazu Ito, Tomoko Oshiro, Hokuto Ohtsuka, Hiroshi Murakami, Hirofumi Aiba   +5 more
doaj   +1 more source

Structural plasticity of the living kinetochore [PDF]

, 2017
The kinetochore is a large, evolutionarily conserved protein structure that connects chromosomes with microtubules. During chromosome segregation, outer kinetochore components track depolymerizing ends of microtubules to facilitate the separation of ...
Akiyoshi, Al-Bassam, Aravamudhan, Aravamudhan, Asbury, Biggins, Biggins, Boris Rubinstein, Brian D. Slaughter, Chan, Cheeseman, Culotti, Daniel, De Wulf, Desai, Duffy, Field, Foley, Gandhi, Gao, Gardner, Gestaut, Grishchuk, Guimaraes, Hartwell, He, Hedges, Hill, Hornung, Hornung, Jaspersen, Jay R. Unruh, Jeffrey J. Lange, Jennifer L. Gerton, Jin, Jin, Joglekar, Joglekar, Joglekar, Joglekar, Karthik Dhatchinamoorthy, Kim, Kosco, Lampert, Liu, Longtine, Mallavarapu, Malvezzi, Manjunatha Shivaraju, Mayer, McAinsh, McIntosh, McKinney, Meng, Mieck, Miller, Miranda, Ng, Obuse, Pavelka, Pearson, Pfau, Podolski, Powers, Ramey, Sarangapani, Schleiffer, Schmidt, Severin, Shivaraju, Smith, Stephens, Su, Suzuki, Tanaka, Tien, Tytell, Umbreit, Usui, van Breugel, van Hooff, Visintin, Walczak, Wang, Welburn, Westermann, Westermann, Winey, Wisniewski, Wolyniak, Yuen   +90 more
core   +1 more source

Label‐free imaging of intracellular structures in living mammalian cells via external apodization phase‐contrast microscopy

The FEBS Journal, EarlyView.
External apodization phase‐contrast (ExAPC) microscopy enables label‐free visualization of diverse intracellular structures in living mammalian cells. By enhancing phase‐contrast imaging through optical apodization, ExAPC reveals fine subcellular details, such as lipid droplets and organelle contacts, without fluorescent labels.
Hiroshi Ohno, Takenori Nishimura, Kenta Kainoh, Yoshitaka Ohashi, Naoko Onodera, Mayuko Kano, Lay Nurhana Sari, Masato Masuda, Yoshiaki Tamura, Teppei Nishino, Yusuke Hayashi, Yusuke Yamamoto, Shin‐Ichiro Takahashi, Yuta Mishima, Yosuke Yoneyama, Yoshinori Takeuchi, Motohiro Sekiya, Takashi Matsuzaka, Takafumi Miyamoto, Hitoshi Shimano   +19 more
wiley   +1 more source

Cytoplasmic microtubule organization in fission yeast [PDF]

Yeast, 2006
AbstractDuring the cell cycle of the fission yeast Schizosaccharomyces pombe, striking changes in the organization of the cytoplasmic microtubule cytoskeleton take place. These may serve as a model for understanding the different modes of microtubule organization that are often characteristic of differentiated higher eukaryotic cells.
Kenneth E, Sawin, P T, Tran
openaire   +2 more sources