Results 101 to 110 of about 83,026 (211)
Mitotic Phosphorylation of Swi6/HP1 Regulates Its Chromatin Binding and Chromosome Segregation
The FASEB Journal, Volume 39, Issue 21, 15 November 2025.Heterochromatin protein 1 (HP1) plays an important role in heterochromatin assembly. HP1 proteins undergo additional phosphorylation during mitosis. However, the functional significance of the mitotic phosphorylation of HP1 remains unclear. We identified mitotic phosphorylation sites within fission yeast Swi6 and showed that this phosphorylation is ...
Yuriko Yoshimura +8 more
wiley +1 more source
Negative Cell Cycle Regulation and DNA Damage-inducible Phosphorylation of the BRCT Protein 53BP1 [PDF]
, 2001 In a screen designed to discover suppressors of mitotic catastrophe, we identified the Xenopus ortholog of 53BP1 (X53BP1), a BRCT protein previously identified in humans through its ability to bind the p53 tumor suppressor.
Carpenter, Phillip B. +3 more
core
Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA [PDF]
, 2015 SMC5/6 is a highly conserved protein complex related to cohesin and condensin, which are the key components of higher-order chromatin structures. The SMC5/6 complex is essential for proliferation in yeast and is involved in replication fork stability and
Adamus, Marek +10 more
core +2 more sources
Interdisciplinary Medicine, Volume 3, Issue 6, November 2025.Background: Mitochondrial fission protein (FIS1), affecting energy metabolism and homeostasis, is crucial for mitochondrial quality control (MQC) and tumor progression. Key Points: It varies in expression across TME, influencing tumor progression.
Chao Wei +7 more
wiley +1 more source
Patterning of polar active filaments on a tense cylindrical membrane
, 2012 We study the dynamics and patterning of polar contractile filaments on the surface of a cylindrical cell using active hydrodynamic equations that incorporate couplings between curvature and filament orientation.
Madan Rao +4 more
core +1 more source
Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.ABSTRACT According to the endosymbiotic theory of mitochondrial origin, an α‐proteobacterium entered a prokaryotic cell and, through symbiosis, evolved into the mitochondria—the powerhouse of the cell. Like other bacteria, the α‐proteobacteria generate their own extracellular vesicles (EVs), a trait that was passed onto the mitochondria, enabling them ...
Rostyslav Horbay +5 more
wiley +1 more source
To Make a Long Spindle Short: Nuclear Envelope Breakdown during Meiosis
Cell Reports, 2018 In fission yeast, the nuclear envelope (NE) remains intact during mitosis and meiosis I but is compromised during meiosis II. In this issue of Cell Reports, Flor-Parra et al.
Joseph M. Varberg, Sue L. Jaspersen
doaj +1 more source
Managing Single-Stranded DNA during Replication Stress in Fission Yeast [PDF]
, 2015 Sarah Sabatinos, Susan L. Forsburg
openalex +1 more source
Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery
PROTEOMICS, Volume 25, Issue 21-22, Page 102-150, November 2025.ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam +12 more
wiley +1 more source
Slm9, a Novel Nuclear Protein Involved in Mitotic Control in Fission Yeast [PDF]
, 2000 Junko Kanoh, Paul Russell
openalex +1 more source