Results 81 to 90 of about 84,111 (254)

Adding phosphorylation events to the core oscillator driving the cell cycle of fission yeast.

PLoS ONE, 2018
Much is known about the regulatory elements controlling the cell cycle in fission yeast (Schizosaccharomyces pombe). This regulation is mainly done by the (cyclin-dependent kinase/cyclin) complex (Cdc2/Cdc13) that activates specific target genes and ...
Dania Humaidan, Frank Breinig, Volkhard Helms   +2 more
doaj   +1 more source

A yeast-based screening assay identifies repurposed drugs that suppress mitochondrial fusion and mtDNA maintenance defects

Disease Models & Mechanisms, 2019
Mitochondria continually move, fuse and divide, and these dynamics are essential for the proper function of the organelles. Indeed, the dynamic balance of fusion and fission of mitochondria determines their morphology and allows their immediate ...
Thomas Delerue, Déborah Tribouillard-Tanvier, Marlène Daloyau, Farnoosh Khosrobakhsh, Laurent Jean Emorine, Gaëlle Friocourt, Pascale Belenguer, Marc Blondel, Laetitia Arnauné-Pelloquin   +8 more
doaj   +1 more source

Parameter identification problems in the modelling of cell motility [PDF]

, 2014
We present a novel parameter identification algorithm for the estimation of parameters in models of cell motility using imaging data of migrating cells.
A Friedman, A Mogilner, AM Stuart, AS Ackleh, AS Ackleh, B Onken, Björn Stinner, C Hogea, C Jiang, C Weston, Cathryn Weston, Chandrasekhar Venkataraman, Charles M. Elliott, CT Kelley, D Bray, D Dormann, DW Marquardt, F Haußer, FD Kelly, G Dziuk, G Dziuk, G Dziuk, G Dziuk, Graham Ladds, H Tatebe, I Hecht, IF Sbalzarini, J Alamo Del, J Barrett, J Barrett, J Nocedal, J Satulovsky, JF Monahan, K Deckelnick, K Deckelnick, L Bosgraaf, M Burger, M Herant, M Lombardi, M Mos, M Neilson, MA Dewar, MA Iglesias, MJ Pittet, MR Garvie, O Lakkis, R Lefever, T Drake, TF Chan, V Isakov, Wayne Croft   +50 more
core   +1 more source

Reduced Oligodendrocyte Density and Axonal Caliber Associated With Mitochondrial Alterations in the White Matter of Chronically‐Starved Mice

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with extreme weight loss, hyperactivity, and amenorrhea. Neuroimaging studies revealed brain atrophy and disruption of white matter integrity in the corpus callosum (CC) of patients with AN. However, the underlying pathophysiological mechanisms remain unclear.
Stephan Lang, Annelie Zimmermann, Kaja Dickert, Hanna Rupprecht, Julia Priebe, Fabienne Haberland, Hanna‐Sophia Henschke, Katharina Schuster, Marcus Frank, Linda Frintrop   +9 more
wiley   +1 more source

Fission yeast: in shape to divide

Current Opinion in Cell Biology, 2012
How are cell morphogenesis and cell cycle coordinated? The fission yeast is a rod-shaped unicellular organism widely used to study how a cell self-organizes in space and time. Here, we discuss recent advances in understanding how the cell acquires and maintains its regular rod shape and uses it to control cell division.
Hachet, Olivier, Bendezú, Felipe O, Martin, Sophie G   +2 more
openaire   +2 more sources

Indistinguishable landscapes of meiotic DNA breaks in rad50+ and rad50S strains of fission yeast revealed by a novel rad50+ recombination intermediate. [PDF]

PLoS Genetics, 2008
The fission yeast Schizosaccharomyces pombe Rec12 protein, the homolog of Spo11 in other organisms, initiates meiotic recombination by creating DNA double-strand breaks (DSBs) and becoming covalently linked to the DNA ends of the break.
Randy W Hyppa, Gareth A Cromie, Gerald R Smith   +2 more
doaj   +1 more source

Regulation of the SUV39H Family Methyltransferases: Insights from Fission Yeast

Biomolecules, 2023
Histones, which make up nucleosomes, undergo various post-translational modifications, such as acetylation, methylation, phosphorylation, and ubiquitylation. In particular, histone methylation serves different cellular functions depending on the location
Rinko Nakamura, Jun-ichi Nakayama
doaj   +1 more source

Bridging the Effects of Noncontact Temperature Sensing and Cellular Biofunctionality in Nanosized Dysprosium(III)‐Doped Fluorapatite

Small, EarlyView.
Multifunctional dysprosium(III) ion–doped fluorapatite nanomaterials combine bioactivity with photoluminescent temperature sensing. The biological studies reveal interactions with progenitor cells, highlighting potential applications in regenerative medicine and tissue engineering, while temperature‐dependent emission of Dy³⁺ ions enables reliable ...
Sara Targonska, Natalia Charczuk, Adam Kabanski, Klaudia Marcinkowska, Joanna Sulecka‐Zadka, Daria Szymanowska, Agnieszka Śmieszek, Rafal J. Wiglusz   +7 more
wiley   +1 more source

Quantification of Mitochondrial Dynamics in Fission Yeast

Bio-Protocol, 2019
Mitochondria are double-membraned organelles responsible for several functions in the cell including energy production, calcium signaling, and cellular metabolism.
Leeba Chacko, Vaishnavi Ananthanarayanan
doaj   +1 more source

The AAA-ATPase Yta4/ATAD1 interacts with the mitochondrial divisome to inhibit mitochondrial fission.

PLoS Biology, 2023
Mitochondria are in a constant balance of fusion and fission. Excessive fission or deficient fusion leads to mitochondrial fragmentation, causing mitochondrial dysfunction and physiological disorders.
Jiajia He, Ke Liu, Yifan Wu, Chenhui Zhao, Shuaijie Yan, Jia-Hui Chen, Lizhu Hu, Dongmei Wang, Fan Zheng, Wenfan Wei, Chao Xu, Chengdong Huang, Xing Liu, Xuebiao Yao, Lijun Ding, Zhiyou Fang, Ai-Hui Tang, Chuanhai Fu   +17 more
doaj   +1 more source