Results 91 to 100 of about 3,683,995 (257)
Impact of fitness cost on reversion rates.
, 2015 In unadjusted survival analysis (“fitness cost”), in survival analysis adjusted for type of mutation (“fitness cost adj.”). Impact of mean fitness cost and residual fitness cost in univariable analysis (“uvar.”) and in multivariable analysis including ...
Jürg Böni (36157) +11 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source
Siberian Journal of Life Sciences and AgricultureBackground. The development of fungicide resistance in the apple scab pathogen suggests the development of measures to manage the development of resistance that can functionally delay the emergence of resistant populations of the pathogen.
Andrei I. Nasonov +3 more
doaj +1 more source
Fitness gains hamper efforts to tackle drug resistance
eLife, 2013 It has long been assumed that resistance to antibiotics reduces the fitness of disease-causing bacteria, but experiments on Salmonella Typhi, the bacteria that causes Typhoid fever, are now challenging this view.
Shanta Dutta
doaj +1 more source
Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph +5 more
wiley +1 more source
, 2013 Dynamics of an Ae. aegypti population subject to continuous male-only R&R releases at a 2∶1 (r = 2) release ratio for one year (T = 365) when there is an additive fitness cost associated with the AP allele.
Kenichi Okamoto (108729) +3 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Advanced ScienceBiotin is an essential cofactor for central metabolic pathways in all organisms. The newly identified BioE‐BioL module constitutes a new biotin biosynthesis pathway, yet its mechanisms remain incompletely characterized.
Meng Zhang +9 more
doaj +1 more source
Changes in Fitness, physical activity, fatness, and screen time: A longitudinal study in children and adolescents [PDF]
, 2009 *_Objective:_* To analyze whether changes in Physical Activity Index (PAI), sedentary time (ST; TV and PC use), and Body Mass Index (BMI) made a significant contribution to longitudinal changes in Physical Fitness (PF) of children and adolescents ...
Clarice Martins +7 more
core
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Arthritis Care &Research, EarlyView.Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai +7 more
wiley +1 more source