Results 51 to 60 of about 2,185,416 (252)

Probability in Biology: The Case of Fitness [PDF]

open access: yes, 2012
I argue that the propensity interpretation of fitness, properly understood, not only solves the explanatory circularity problem and the mismatch problem, but can also withstand the Pandora’s box full of problems that have been thrown at it.
Millstein, Roberta L.
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Costs of Insecticide Resistance on Fitness [PDF]

open access: yes, 2021
The mechanisms behind insecticide resistance are commonly thought to induce fitness costs in the absence of insecticides in the environment. However, it is still largely unknown how these fitness costs present themselves and what factors may influence ...
Brown, Dylan
core   +1 more source

Kansas Fitness Week, May 1-9, 1982 : fitness is for everybody

open access: yes, 1982
"Sponsored by the Governor's Council on Fitness"--Page 6Fitness is for Every Body -- Kansas Fitness Week May 1-9, 1982 -- Celebrate Fitness -- Governor's Cup Running Events -- Capitol Runs -- Regional Runs -- Guidelines to Success -- 1981 Project Sites --
Governor's Council on Fitness
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Inheritance and Fitness Costs of Laboratory-Selected Cry1Ab Resistance in Ostrinia furnacalis

open access: yesAgronomy
The Asian corn borer, Ostrinia furnacalis, is a major pest in China and across East and Southeast Asia, serving as the primary target of Bt maize expressing Cry proteins.
Houjun Xia   +3 more
doaj   +1 more source

Adaptive Evolution Compensated for the Plasmid Fitness Costs Brought by Specific Genetic Conflicts

open access: yesPathogens, 2023
New Delhi metallo-β-lactamase (NDM)-carrying IncX3 plasmids is important in the transmission of carbapenem resistance in Escherichia coli. Fitness costs related to plasmid carriage are expected to limit gene exchange; however, the causes of these fitness
Feifeng Li   +11 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

open access: yesEmerging Infectious Diseases, 2012
In Belgium, decreasing macrolide, lincosamide, streptogramins B, and tetracycline use during 1997–2007 correlated significantly with decreasing macrolide-resistant Streptococcus pyogenes during 1999–2009.
Liesbet Van Heirstraeten   +5 more
doaj   +1 more source

Successfully resisting a pathogen is rarely costly in Daphnia magna [PDF]

open access: yes, 2010
Background A central hypothesis in the evolutionary ecology of parasitism is that trade-offs exist between resistance to parasites and other fitness components such as fecundity, growth, survival, and predator avoidance, or resistance to other parasites.
Pedro F Vale   +9 more
core   +1 more source

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