Results 51 to 60 of about 177,487 (332)

Fixed-time input-to-state stability and applications to fixed-time sliding mode control

International Journal of Control
This paper investigates the robust stability properties of two simple fixed-time stabilizing controls tailored for scalar systems. These algorithms require a small amount of tuning parameter providing fixed-time stability, and ensuring trajectory robustness against disturbances and/or measurement noise.
Labbadi, Moussa, Efimov, Denis
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Vibrational Modal Frequencies and Shapes of Two-Span Continuous Timber Flooring Systems [PDF]

, 2019
Based on classic vibrational bending theory on beams, this paper provides comprehensive analytical formulae for dynamic characteristics of two equal span continuous timber flooring systems, including frequency equations, modal frequencies, and modal ...
Kilpatrick, Tony, Zhang, Binsheng
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Robust Simulation for Hybrid Systems: Chattering Path Avoidance [PDF]

, 2015
The sliding mode approach is recognized as an efficient tool for treating the chattering behavior in hybrid systems. However, the amplitude of chattering, by its nature, is proportional to magnitude of discontinuous control.
Aljarbouh, Ayman, Caillaud, Benoit
core   +5 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The adaptive control system of quadrocopter motion [PDF]

, 2018
In this paper we present a system for automatic control of a quadrocopter based on the adaptive control system. The task is to ensure the motion of the quadrocopter along the given route and to control the stabilization of the quadrocopter in the air in ...
Schaerf, Marco, Vinokursky, Dmitry, Mecella, Massimo, Samoilov, Filipp   +3 more
core   +4 more sources

Disturbance observer based fixed time sliding mode control for a class of uncertain second-order nonlinear systems

AIMS Mathematics
This study investigates the fixed-time control problem for a class of second-order nonlinear systems. Acknowledging that most existing fixed-time sliding mode controllers encounter singularity issues, this paper aims to design a non-singular fixed-time ...
Zhiqiang Chen, Alexander Yurievich Krasnov   +1 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Global Fixed-Time Horizontal Tracking Control of AUV Under Parameter Perturbation and Input Quantization

IEEE Access
This paper investigates the horizontal trajectory tracking problem of an autonomous underwater vehicle (AUV) subject to parameter perturbations and ocean current disturbances. A fixed-time integral sliding mode control method is proposed, incorporating a
Sunwei Jiang, Shuxuan Liu, Zhicheng Liu, Quanming Miao   +3 more
doaj   +1 more source