Results 61 to 70 of about 1,967,755 (312)

Stock Market Participation, Portfolio Choice and Pensions over the Life-cycle [PDF]

open access: yes, 2007
In this paper we present a calibrated life-cycle model is able to simultaneously match asset allocations and stock market participation profiles over the life-cycle.
Ball, Steffan
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Daily Costs and Cost Effectiveness of Glaucoma Fixed Combinations in China

open access: yesJournal of Ophthalmology, 2020
Background. The aim of this study was to compare the daily costs and cost effectiveness of fixed combination glaucoma drugs in China. Methods. This study included the following fixed combination drugs: brinzolamide 1% and timolol 0.5% (Azarga; Alcon, Inc.
Chenjia Xu   +4 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

The Relationship between Sparseness and Energy Consumption of Neural Networks

open access: yesNeural Plasticity, 2020
About 50-80% of total energy is consumed by signaling in neural networks. A neural network consumes much energy if there are many active neurons in the network. If there are few active neurons in a neural network, the network consumes very little energy.
Guanzheng Wang   +3 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Determination of Total Costs, Labour Requirements and Work Efficiencies in Second Fodder Corn Silage Production at Bafra Town of Samsun

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2016
This study was completed with the aim of determining work efficiencies, labour requirement, and total cost of second fodder corn silage agricultural enterprises on flat ground in Bafra district of Samsun province. According to the results, total variable
Taner Yıldız
doaj   +1 more source

VARIABLE AND FIXED COSTS IN COMPANY MANAGEMENT [PDF]

open access: yes
The cost absorbs all the expenses of production for a company at acertain level of the activity. For eliminating the influence of the fixed costs’sabsorbtion and for a better supervision of other causes of digressions, the managerscan apply the method of
Sorin Briciu
core  

Talep belirsizliğinin Türk imalat firmalarının maliyet yapısı üzerindeki etkisi [PDF]

open access: yes, 2018
Cost rigidity defines the characteristics of cost structure which is defined as the proportion of fixed costs to variable costs of firms. When the proportion of fixed costs are higher than the variable costs, then the cost structure is defined as a rigid
Uyar, Umut, Özkaya, Hakan
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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