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Telitacicept versus belimumab in proliferative lupus nephritis. [PDF]
Wang C +6 more
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Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11. [PDF]
Miao S +12 more
europepmc +1 more source
The cyclase-associated protein contributes to antifungal susceptibility and virulence in <i>Aspergillus fumigatus</i>. [PDF]
Yang X +7 more
europepmc +1 more source
Machine learning-based predictive model for the perioperative co-occurrence of T-cell-mediated rejection and pneumonia in liver transplantation. [PDF]
Sun J +5 more
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Evaluation of cyclophosphamide for steroid-refractory hepatic acute graft-vs-host disease after allogeneic hematopoietic stem cell transplantation. [PDF]
Lu N +14 more
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Journal of Pharmacology and Experimental Therapeutics, 1999
The neurotrophic property of the immunosuppressant drug FK506 (tacrolimus) is believed to depend on the 12-kDa FK506-binding protein (FKBP-12). Here, we show that FK506 maintains its neurotrophic activity in primary hippocampal cell cultures from FKBP-12 knockout mice.
Bruce G Gold +2 more
exaly +3 more sources
The neurotrophic property of the immunosuppressant drug FK506 (tacrolimus) is believed to depend on the 12-kDa FK506-binding protein (FKBP-12). Here, we show that FK506 maintains its neurotrophic activity in primary hippocampal cell cultures from FKBP-12 knockout mice.
Bruce G Gold +2 more
exaly +3 more sources
Crystal Structure of the FK506 Binding Domain of Plasmodium falciparum FKBP35 in Complex with FK506
The emergence of multi-drug-resistant strains of Plasmodium parasites has prompted the search for alternative therapeutic strategies for combating malaria. One possible strategy is to exploit existing drugs as lead compounds. FK506 is currently used in the clinic for preventing transplant rejection.
Ye, H +7 more
openaire +6 more sources

