Results 111 to 120 of about 465,086 (299)

Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome

open access: yesArthritis &Rheumatology, EarlyView.
Objective VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani   +10 more
wiley   +1 more source

Expert Perspectives: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

open access: yesArthritis &Rheumatology, EarlyView.
Treat‐to‐target has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal treat‐to‐target framework for adult IIM has not yet been ...
Shiri Keret   +2 more
wiley   +1 more source

Exploring the Potential of Cluster Analysis in Identifying Disease Phenotypes in Calcium Pyrophosphate Deposition: Moving From Intuition to Insight

open access: yesArthritis &Rheumatology, EarlyView.
Objective Calcium pyrophosphate deposition (CPPD) disease is a heterogeneous condition and is frequently misdiagnosed due to the different clinical presentations and variable disease progression. Aim of this study is to identify clinical phenotypes of CPPD disease by integrating real‐world data from two data sets. Methods Data from the COLCHICORT trial
Greta Pellegrino   +20 more
wiley   +1 more source

The Kinematic Signature of the Warp and Waves in the Milky Way Disk

open access: yesThe Astrophysical Journal
Using over 170,000 red clump (RC) stars selected from LAMOST and APOGEE, we conduct a detailed analysis of the stellar V _Z as a function of L _Z (or R _g ) across different ϕ bins for various disk populations.
Weixiang Sun   +3 more
doaj   +1 more source

Outcomes of Tapering Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs in Rheumatoid Arthritis: A Multicenter Randomized Noninferiority Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective Evidence supporting tapering of biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in patients with rheumatoid arthritis (RA) with sustained low disease activity (LDA) remains limited. We evaluated the efficacy and safety of a structured b/tsDMARD‐tapering strategy in patients with RA who had achieved sustained ...
Dong‐Jin Park   +19 more
wiley   +1 more source

Characterizing Temperatures of Flares on the M Dwarf Wolf 359 from Simultaneous Multiband Optical Observations

open access: yesThe Astronomical Journal
We present a flare temperature study of the highly active M dwarf Wolf 359 using simultaneous multiband ( u , g , r , i , and z ) photometric observations from the Lulin 1 m and 41 cm telescopes.
Chia-Lung Lin   +4 more
doaj   +1 more source

Search for Flare Stars in TAOS Data

open access: yes, 2007
中美掩星觀測計畫的目標為測量彗星核大小至幾公里的古柏帶天體之數量與大小分佈。在毎個晴朗的夜晚,超過數百顆背景恆星由三台寬視野(3平方度)、短焦比(f/1.9)、小口徑(50公分)且配備有2k×2k CCD 相機的望遠鏡自動監控。在三台望遠鏡同時操作下,誤報率可因此降低。資料取樣頻率為5 Hz,孔徑測光可至星等約為13.7等的背景恆星。 儘管 TAOS 是為偵測掩星事件而設計,其龐大的資料量與短暫的曝光時間提供了可用於搜尋快速變化之變星的資料庫。由於毎隔0.2秒記錄一次背景恆星的光通量 ...
Liu, Chu-Hsin, 劉筑欣
core  

All‐Inside Anterior Cruciate Ligament Reconstruction Using Semitendinosus Autograft Augmented With Biocomposite Scaffold: A Technical Note

open access: yesArthroscopy Techniques, EarlyView.
Abstract Anterior cruciate ligament reconstruction using the all‐inside technique offers bone preservation and minimal invasiveness. However, single hamstring tendon autografts with a diameter below 8 mm carry increased failure risk. BioBrace (ConMed), a biocomposite scaffold of bioresorbable poly(L‐lactide) microfilaments and type I collagen, provides
Abdullah Alanazi   +4 more
wiley   +1 more source

Role of Nonthermal Processes in the Quiescent and Active Millimeter Spectrum of a Young M Dwarf

open access: yesThe Astrophysical Journal
Millimeter (mm) emission from F-M dwarfs (cool stars) primarily traces chromospheric activity, with thermal emission thought to dominate in quiescence. Despite the high chromospheric activity, the quiescent mm spectral fluence (mm- S ( ν )) of young (1 ...
Atul Mohan   +5 more
doaj   +1 more source

Comparative Statistics of Solar Flares and Flare Stars

open access: yesSolar Physics
Abstract The distribution of interval times between recurrent discrete events, such as Solar and stellar flares, reflects their underlying dynamics. Log-normal functions provide good fits to the interval time distributions of many astronomical processes.
Jonathan Katz   +3 more
openaire   +2 more sources

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