Results 141 to 150 of about 39,486 (294)

Anifrolumab Treatment Leads to Rapid Reduction in Urinary Biomarkers of Intrarenal Inflammation in Lupus Nephritis: Results from the Phase 2 TULIP‐LN Trial

Arthritis &Rheumatology, Accepted Article.
Objectives Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE) and is partially driven by type I interferon (IFN) signaling. Anifrolumab, an approved treatment for patients with SLE, has been investigated in a phase 2 trial in patients with LN receiving standard therapy (TULIP‐LN, NCT02547922). We studied
Andrea Fava, Michelle Petri, Patrick G. Gavin, Eszter Csomor, Philip Z. Brohawn, Daniel Muthas, Adam Platt, Catharina Lindholm, Nicola Ferrari   +8 more
wiley   +1 more source

Stellar flares

Living Reviews in Solar Physics
Magnetic storms on stars manifest as remarkable, randomly occurring changes of the luminosity over durations that are tiny in comparison to the normal evolution of stars.
Adam F. Kowalski
doaj   +1 more source

Treatment of a large cohort of childhood chronic non‐infectious uveitis a multicentric large study: adalimumab versus methotrexate as first line therapy

Arthritis &Rheumatology, Accepted Article.
Background Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in Juvenile Idiopathic Arthritis associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheuma/ophthalmology units at Florence and Bristol.
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source

Wachmann's flare star

The Astronomical Journal, 1954
W. J. Luyten, Dorrit Hoffleit
openaire   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated with Colchicine Prophylaxis

Arthritis &Rheumatology, Accepted Article.
Objective This study investigated that serum metabolomics, prior to ULT initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n=409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun, Lingfang Xu, Haibing Chen, Mingshu Sun, Zhiqiang Li, Rui Li, Lidan Ma, Hui Zhang, Aichang Ji, Yuwei He, Na Wu, Le Yan, Robert Terkeltaub, Changgui Li   +13 more
wiley   +1 more source

A multifaceted interplay between hemophagocytosis, IL‐18 and type I IFN distinguishes Still disease from other autoinflammatory diseases

Arthritis &Rheumatology, Accepted Article.
Objectives The unknown pathophysiology and the lack of specific features for systemic Juvenile Idiopathic arthritis and adult‐onset Still disease (collectively Still disease/SD) delays diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory diseases ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G.B. Grashof, Laurie Vaillant, Renske J.H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, ImmunAID consortium, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +17 more
wiley   +1 more source

Investigating Possible Stellar Coronal Mass Ejections in M-type Dwarfs Using the CARMENES Data Release 1 Spectra

The Astrophysical Journal
Stellar coronal mass ejections (CMEs) have significant impacts on surrounding exoplanets and stellar evolution. For M-type dwarf stars, hosting close-in habitable zones, frequent and intense stellar CMEs may render their potentially habitable planets ...
Dongtao Cao, Shenghong Gu
doaj   +1 more source

Repeating Nuclear Transients From Repeating Partial Tidal Disruption Events

Astronomische Nachrichten, EarlyView.
ABSTRACT Extragalactic nuclear transients that exhibit repeating outbursts can be modeled as the repeated dynamical interaction between bound stars and supermassive black holes (SMBHs). A subset of these transients, with recurrence timescales of months‐to‐years, have been explained as accretion flares from the repeated tidal stripping of a star by an ...
Ananya Bandopadhyay, Eric R. Coughlin, Julia Fancher, C. J. Nixon, Dheeraj R. Pasham   +4 more
wiley   +1 more source

A 7 Day Multiwavelength Flare Campaign on AU Mic. IV. Quiescent Gyrosynchrotron and Gyroresonance Radiation from 12 to 25 GHz

The Astrophysical Journal
We present an analysis of the radio quiescent data from a multiwavelength campaign of the active M dwarf flare star AU Mic (dM1e) that occurred in 2018 October. Using Ku -band data (12–18 GHz) from the Karl G. Jansky Very Large Array and K -band data (17–
Isaiah I. Tristan, Rachel A. Osten, Yuta Notsu, Adam F. Kowalski, Steven R. Cranmer   +4 more
doaj   +1 more source

Lithium in flare stars [PDF]

Monthly Notices of the Royal Astronomical Society, 1981
R. de La Reza, C. A. O. Torres, I. C. Busko   +2 more
openaire   +1 more source