Results 41 to 50 of about 517,787 (283)

A review of the impact of FLASH radiotherapy on the central nervous system and glioma

Radiation Medicine and Protection, 2022
Glioma has received considerable attention because of its potential of inducing high rates of morbidity, disability, and mortality. FLASH radiotherapy (FLASH-RT) has emerged as a popular topic in current research because of its ability to protect normal ...
Lin Li, Yayi Yuan, Yahui Zuo
doaj   +1 more source

An insight into hypothesized biological mechanisms contributing to the Flash effect

Frontiers in Physics, 2023
In recent years, FLASH radiotherapy (FLASH RT) has gained attention in preclinical studies as a potential advancement in cancer treatment. The great advantage of FLASH RT is the ultra-fast, high doses delivery that have a similar or greater effect on ...
Francesca Del Debbio, Maria Sofia Bertilacchi, Alessandra Gonnelli, Alessandra Gonnelli, Eleonora Da Pozzo, Eleonora Da Pozzo, Eleonora Da Pozzo, Valentina Tozzini, Valentina Tozzini, Claudia Martini, Claudia Martini, Claudia Martini, Simone Capaccioli, Simone Capaccioli, Simone Capaccioli, Barbara Costa, Barbara Costa   +16 more
doaj   +1 more source

Innovations a l'Institut d'automatique - Le tele-enseignement pour la formation pratique des ingenieurs

, 2023
LAThis was published in the EPFL internal newspaper "Flash" and so no author ...
EPFL, Flash
core  

Trois nouveaux maitres d'enseignement et de recherche (MER) - Automatique

, 2023
LAThis was published in the EPFL internal newspaper "Flash" and so no author ...
EPFL, Flash
core  

Comparable survival in rats with intracranial glioblastoma irradiated with single-fraction conventional radiotherapy or FLASH radiotherapy

Frontiers in Oncology
BackgroundRadiotherapy increases survival in patients with glioblastoma. However, the prescribed dose is limited by unwanted side effects on normal tissue.
Emma Liljedahl, Elise Konradsson, Karin Linderfalk, Emma Gustafsson, Kristoffer Petersson, Kristoffer Petersson, Crister Ceberg, Henrietta Nittby Redebrandt, Henrietta Nittby Redebrandt   +8 more
doaj   +1 more source

FLASH radiotherapy: Research process from basic experimentation to clinical application

Precision Radiation Oncology, 2021
FLASH radiotherapy (FLASH‐RT) has gained attention as an ultra‐high dose rate RT in recent years. This treatment significantly shortens the time of RT and reduces the influence of tumor movement caused by breathing or other factors.
Xiaohui Wang, Hui Luo, Xiaoli Zheng, Hong Ge   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation of single-fraction high dose FLASH radiotherapy in a cohort of canine oral cancer patients

Frontiers in Oncology, 2023
BackgroundFLASH radiotherapy (RT) is a novel method for delivering ionizing radiation, which has been shown in preclinical studies to have a normal tissue sparing effect and to maintain anticancer efficacy as compared to conventional RT.
Betina Børresen, Maja L. Arendt, Elise Konradsson, Kristine Bastholm Jensen, Sven ÅJ. Bäck, Per Munck af Rosenschöld, Crister Ceberg, Kristoffer Petersson, Kristoffer Petersson   +8 more
doaj   +1 more source

Exploring Design Dimensions in Flash-based Mass-memory Devices [PDF]

, 2009
Mission-critical space system applications present several issues: a typical one is the design of a mass-memory device (i.e., a solid- state recorder).
Caramia, M., Caramia M., Fabiano, Michele, Prinetto, Paolo Ernesto, Di Carlo, Stefano   +4 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source