Results 31 to 40 of about 517,787 (283)

Ultrahigh Dose-rate Radiotherapy: Next Steps for FLASH-RT [PDF]

Clinical Cancer Research, 2019
Abstract A new way of delivering radiotherapy at very high dose rates is described and compared with conventional radiotherapy. The ultrahigh dose-rate therapy reduces damage to normal pig skin and exerts potent activity against spontaneous nasal tumors in cat patients.
openaire   +3 more sources

Simulation study of a novel small animal FLASH irradiator (SAFI) with integrated inverse-geometry CT based on circularly distributed kV X-ray sources

Scientific Reports, 2023
Ultra-high dose rate (UHDR) radiotherapy (RT) or FLASH-RT can potentially reduce normal tissue toxicity. A small animal irradiator that can deliver FLASH-RT treatments similar to clinical RT treatments is needed for pre-clinical studies of FLASH-RT.
Yuewen Tan, Shuang Zhou, Jonathan Haefner, Qinghao Chen, Thomas R. Mazur, Arash Darafsheh, Tiezhi Zhang   +6 more
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Flash Radiotherapy: Innovative Cancer Treatment

Encyclopedia, 2023
Flash radiotherapy (Flash-RT) is an innovative technique used in radiotherapy for cancer treatment because it delivers an extremely high dose of radiation (>40 Gy/s) to the tumour in a very short period of time, typically within a fraction of a second ...
James C. L. Chow, Harry E. Ruda
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A Modified Lethal and Potentially Lethal Model With Explicit Oxygen Tension Dependence for FLASH RT [PDF]

International Journal of Radiation Oncology*Biology*Physics, 2021
Purpose/Objective(s) To modify Curtis Lethal and Potentially Lethal (LPL) model to extend it from conventional (CONV) to ultra-high dose rate (FLASH) Radiotherapy (RT) domain with explicit intracellular oxygen tension dependence. Materials/Methods After combining radiation-induced oxygen depletion, oxygen fixation hypothesis, and the Oxygen ...
S.M. Zhou, Y. Yan, D. Zheng, S. Wang, S.B. Wisnoskie, D. Umstadter   +5 more
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EDACs and test integration strategies for NAND flash memories [PDF]

, 2010
Mission-critical applications usually presents several critical issues: the required level of dependability of the whole mission always implies to address different and contrasting dimensions and to evaluate the tradeoffs among them. A mass-memory device
Piazza, R., Stefano Di Carlo, Michele Fabiano, Politecnico Di Torino, Fabiano, Michele, Paolo Prinetto, Prinetto, Paolo Ernesto, Roberto Piazza, Piazza R., Di Carlo, Stefano   +9 more
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Comparable Long-Term Tumor Control for Hypofractionated FLASH Versus Conventional Radiation Therapy in an Immunocompetent Rat Glioma Model

Advances in Radiation Oncology, 2022
Purpose: To ensure a clinical translation of FLASH radiation therapy (FLASH-RT) for a specific tumor type, studies on tumor control and toxicity within the same biological system are needed.
Elise Konradsson, MSc, Emma Liljedahl, MD, Emma Gustafsson, MSc, Gabriel Adrian, MD, PhD, Sarah Beyer, MSc, Suhayb Ehsaan Ilaahi, MSc, Kristoffer Petersson, PhD, Crister Ceberg, PhD, Henrietta Nittby Redebrandt, MD, PhD   +8 more
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Key changes in the future clinical application of ultra-high dose rate radiotherapy

Frontiers in Oncology, 2023
Ultra-high dose rate radiotherapy (FLASH-RT) is an external beam radiotherapy strategy that uses an extremely high dose rate (≥40 Gy/s). Compared with conventional dose rate radiotherapy (≤0.1 Gy/s), the main advantage of FLASH-RT is that it can reduce ...
Binwei Lin, Mi Fan, Tingting Niu, Yuwen Liang, Haonan Xu, Wenqiang Tang, Xiaobo Du   +6 more
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Flash-X/Flash-X-Test: Tools for testing Flash-X

, 2023
Tools for testing Flash-
Akash Dhruv, Youngjun Lee, Rajeev Jain, Klaus   +3 more
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Mechanisms underlying FLASH radiotherapy, a novel way to enlarge the differential responses to ionizing radiation between normal and tumor tissues

Radiation Medicine and Protection, 2020
Different from conventional radiotherapy (CONV-RT), FLASH radiotherapy (FLASH-RT) delivers a single high dose at a mean dose rate ≥40 ​Gy/s in milliseconds to achieve similar tumor control to CONV-RT while sparing normal tissues from detrimental injury ...
Guangming Zhou
doaj   +1 more source

Long-term anti-tumor effects following both conventional radiotherapy and FLASH in fully immunocompetent animals with glioblastoma

Scientific Reports, 2022
Radiotherapy can induce an immunological response. One limiting factor is side effects on normal tissue. Using FLASH radiotherapy, side effects could possibly be reduced.
Emma Liljedahl, Elise Konradsson, Emma Gustafsson, Karolina Förnvik Jonsson, Jill K. Olofsson, Crister Ceberg, Henrietta Nittby Redebrandt   +6 more
doaj   +1 more source