Results 21 to 30 of about 10,227,314 (240)

EDACs and test integration strategies for NAND flash memories [PDF]

, 2010
Mission-critical applications usually presents several critical issues: the required level of dependability of the whole mission always implies to address different and contrasting dimensions and to evaluate the tradeoffs among them. A mass-memory device
Piazza, R., Stefano Di Carlo, Michele Fabiano, Politecnico Di Torino, Fabiano, Michele, Paolo Prinetto, Prinetto, Paolo Ernesto, Roberto Piazza, Piazza R., Di Carlo, Stefano   +9 more
core   +1 more source

Flash-X/Flash-X-Test: Tools for testing Flash-X

, 2023
Tools for testing Flash-
Akash Dhruv, Youngjun Lee, Rajeev Jain, Klaus   +3 more
core   +1 more source

FLASH Irradiation Spares Lung Progenitor Cells and Limits the Incidence of Radio-induced Senescence

, 2020
PURPOSE: One of the main limitations to anticancer radiotherapy lies in irreversible damage to healthy tissues located within the radiation field.
Heinrich, Sophie, Leboucher, Sophie, Curras-Alonso, Sandra, Bohec, Mylène, Beddok, Arnaud, Karakurt, Hamza Umut, Verrelle, Pierre, Fouillade, Charles, Vooijs, Marc, Dutreix, Marie, Quelennec, Eddy, Bonnet-Boissinot, Sarah, Favaudon, Vincent, Baulande, Sylvain, Londoño-Vallejo, Arturo, Giuranno, Lorena   +15 more
core   +1 more source

Ultra-High Dose Rate FLASH Irradiation Induced Radio-Resistance of Normal Fibroblast Cells Can Be Enhanced by Hypoxia and Mitochondrial Dysfunction Resulting From Loss of Cytochrome C

Frontiers in Cell and Developmental Biology, 2021
Ultra-high dose rate FLASH irradiation (FLASH-IR) has got extensive attention since it may provide better protection on normal tissues while maintain tumor killing effect compared with conventional dose rate irradiation.
Jintao Han, Zhusong Mei, Chunyang Lu, Jing Qian, Yulan Liang, Xiaoyi Sun, Zhuo Pan, Defeng Kong, Shirui Xu, Zhipeng Liu, Ying Gao, Guijun Qi, Yinren Shou, Shiyou Chen, Zhengxuan Cao, Ye Zhao, Chen Lin, Yanying Zhao, Yixing Geng, Jiaer Chen, Xueqing Yan, Xueqing Yan, Wenjun Ma, Gen Yang   +23 more
doaj   +1 more source

The dresden platform is a research hub for ultra-high dose rate radiobiology

Scientific Reports, 2023
The recently observed FLASH effect describes the observation of normal tissue protection by ultra-high dose rates (UHDR), or dose delivery in a fraction of a second, at similar tumor-killing efficacy of conventional dose delivery and promises great ...
Josefine Metzkes-Ng, Florian-Emanuel Brack, Florian Kroll, Constantin Bernert, Stefan Bock, Elisabeth Bodenstein, Michael Brand, Thomas E. Cowan, René Gebhardt, Stefan Hans, Uwe Helbig, Felix Horst, Jeannette Jansen, Stephan D. Kraft, Mechthild Krause, Elisabeth Leßmann, Steffen Löck, Jörg Pawelke, Thomas Püschel, Marvin Reimold, Martin Rehwald, Christian Richter, Hans-Peter Schlenvoigt, Ulrich Schramm, Michael Schürer, Joao Seco, Emília Rita Szabó, Marvin E. P. Umlandt, Karl Zeil, Tim Ziegler, Elke Beyreuther   +30 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Factors Influencing the Biological Effects of FLASH Irradiation

Antioxidants
Among the methods for increasing the specificity of tumor radiotherapy, FLASH radiotherapy (FLASH-RT) stands out, having recently entered clinical trials.
Sergey Igorevich Glukhov, Elena Ananievna Kuznetsova, Sergey Vsevolodovich Akulinichev   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

FLASH radiotherapy combined with immunotherapy: From biological mechanisms to blockbuster therapeutics

Translational Oncology
FLASH ultra-high dose rate radiotherapy (RT) can effectively exert the protective effect on normal tissue and reduce the risk of treatment-related toxicity, without compromising the killing effect on tumor tissue, resulting in a significant differential ...
Yu Wang, Shu-Nan Qi, Nan Bi, Ye-Xiong Li
doaj   +1 more source