Results 31 to 40 of about 10,227,314 (240)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Increased spread of global flash droughts threatens vegetation productivity resilience
Nature CommunicationsFlash drought (faster-developing drought) has been pervasively intensified, posing detrimental constraints on vegetation productivity. However, the potential expansion of flash droughts from flash drought hotspots to non-hotspots and its associated risks
Renjie Guo +9 more
doaj +1 more source
Exploring Design Dimensions in Flash-based Mass-memory Devices [PDF]
, 2009 Mission-critical space system applications present several issues: a typical one is the design of a mass-memory device (i.e., a solid- state recorder).
Caramia, M. +4 more
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Frontiers in Physics, 2023 The FLASH effect is a radiobiological phenomenon that has garnered considerable interest in the clinical field. Pre-clinical experimental studies have highlighted its potential to reduce side effects on healthy tissues while maintaining isoeffectiveness ...
F. Di Martino +31 more
doaj +1 more source
Effects of self-generation of a flash with action on the flash-grab effect
, 2020 When a stimulus (flash) is briefly presented at the moment when a direction of motion in background texture changes, the perceived position of the stimulus is likely to be biased toward the following motion direction.
Takumi Tanaka
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Flash: The International Short-Short Story Magazine, 12.1 (April 2024) [PDF]
Founded 2008, Flash: The International Short-Short Story Magazine is a biannual literary periodical publishing flash fictions of up to 360 words ...
Chantler, Ashley, Blair, Peter
core +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Flash-memories in Space Applications: Trends and Challenges [PDF]
, 2009 Nowadays space applications are provided with a processing power absolutely overcoming the one available just a few years ago. Typical mission-critical space system applications include also the issue of solid-state recorder(s).
Caramia, M. +4 more
core