Results 51 to 60 of about 194,970 (290)
Temporal errors: Researchers should stop studying the flash-lag effect [PDF]
, 2023 Recent theorizing about perceptual phenomena has been strongly influenced by predictive processing frameworks, to the extent that inconsistent evidence is commonly neglected.
Alex O. Holcombe, Joshua Corbett
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in Physics, 2020 Various in vivo experimental works carried out on different animals and organs have shown that it is possible to reduce the damage caused to healthy tissue still preserving the therapeutic efficacy on the tumor tissue, by drastically reducing the total ...
Fabio Di Martino +15 more
doaj +1 more source
Flash Gas Bypass Method for Improving Performance of an A/C System With a Microchannel Evaporator [PDF]
, 2012 This paper demonstrates that Flash Gas Bypass (FGB) method significantly improved the performances of the microchannel evaporator and the system, compared to the conventional direct expansion (DX) system.
Hrnjak, Predrag S., Tuo, Hanfei
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A framework for the analysis of the influence of rainfall spatial organization and basin morphology on flood response [PDF]
, 2013 This work describes the derivation of a set of statistics, termed spatial moments of catchment rainfall, that quantify the dependence between rainfall spatial organization, basin morphology and runoff response.
Zoccatelli, Davide
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Quantum Beam ScienceThe global cancer burden continues to increase worldwide. Among the various treatment options, radiotherapy (RT), which employs high-energy ionizing radiation to destroy cancer cells, is one of the primary modalities for cancer.
Chang Cheng +7 more
doaj +1 more source
Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?
Frontiers in Oncology, 2020 Radiotherapy is a cornerstone of both curative and palliative cancer care. However, radiotherapy is severely limited by radiation-induced toxicities. If these toxicities could be reduced, a greater dose of radiation could be given therefore facilitating ...
Joseph D. Wilson +4 more
doaj +1 more source