Results 91 to 100 of about 71,504 (306)

Reimagining Lignin Valorization: Synthetic Biology–Enabled Sustainable Aromatic Carbon Biomanufacturing

Advanced Science, EarlyView.
The diagram illustrates a sustainable model of lignin valorization and carbon cycling based on microbial cell factories. Using lignin as the feedstock, synthetic biology technologies, including depolymerization, cell factory construction, pathway gene module integration, and metabolic network regulation, are applied to convert lignin into bulk ...
Na Li, Jun‐Jie Zhangyang, Bing‐Zhi Li, Zhi‐Hua Liu, Ying‐Jin Yuan   +4 more
wiley   +1 more source

Synthesis of rigidified flavin–guanidinium ion conjugates and investigation of their photocatalytic properties

Beilstein Journal of Organic Chemistry, 2009
Flavin chromophores can mediate redox reactions upon irradiation by blue light. In an attempt to increase their catalytic efficacy, flavin derivatives bearing a guanidinium ion as oxoanion binding site were prepared.
Harald Schmaderer, Mouchumi Bhuyan, Burkhard König   +2 more
doaj   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis

Nature, 2015
Ubiquinone (also known as coenzyme Q) is a ubiquitous lipid-soluble redox cofactor that is an essential component of electron transfer chains. Eleven genes have been implicated in bacterial ubiquinone biosynthesis, including ubiX and ubiD, which are ...
M. White, Karl Payne, K. Fisher, S. Marshall, David Parker, N. Rattray, D. Trivedi, R. Goodacre, S. Rigby, N. Scrutton, Sam Hay, D. Leys   +11 more
semanticscholar   +1 more source

Cell Non-Autonomous Activation of Flavin-containing Monooxygenase Promotes Longevity and Healthspan

Science, 2015
Aging: All in the head—and the gut The effects of hypoxia and caloric restriction, both of which extend life span in Caenorhabditis elegans, converge on the activation of an enzyme in cells of the intestine. Leiser et al.
S. Leiser, Hillary A. Miller, Ryan Rossner, Marissa Fletcher, Alison Leonard, Melissa Primitivo, Nicholas D. Rintala, Fresnida J. Ramos, Dana L. Miller, M. Kaeberlein   +9 more
semanticscholar   +1 more source

Stimuli-Responsive Luminescence of an Amphiphilic Flavin Derivative via Thermodynamic and Kinetic Aggregation in Water

Photochem
In this study, we investigated environmentally responsive photoluminescence color changes in water using an amphiphilic flavin derivative (1a) functionalized with an alkylsulfonate group.
Soichiro Kawamorita, Koyo Okamoto, Shufang Huang, Takeshi Naota   +3 more
doaj   +1 more source

Protomer-Dependent Electronic Spectroscopy and Photochemistry of the Model Flavin Chromophore Alloxazine

Molecules, 2018
Flavin chromophores play key roles in a wide range of photoactive proteins, but key questions exist in relation to their fundamental spectroscopic and photochemical properties.
Edward Matthews, Rosaria Cercola, Caroline E. H. Dessent   +2 more
doaj   +1 more source

Entdeckung eines antiviralen Elektronentransferprozesses zur Erzeugung katalytisch selbstversorgender viraler Restriktionsfaktoren

Angewandte Chemie, EarlyView.
CYB5R3 wird als mutmaßlicher Elektronentransferpartner von Viperin (RSAD2) identifiziert, was erklärt, warum die ER‐Lokalisation für die antivirale Aktivität erforderlich ist. Dieses Wissen ermöglichte die Entwicklung immunstiller, katalytisch selbstversorgender antiviraler Restriktionsfaktor‐Enzyme (iCAREs), die ein antivirales Nukleosidtriphosphat ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source

C5-alkyl and C5-aryl Substituted 5-Deazaflavin as Sensitizers for Photodehalogenation of Aryl Halides

Molecules
Aryl halides are important intermediates for chemical synthesis. However, the negative reduction potential up to −2.7 V (vs. SCE) makes photoredox conversion of aryl halides by reductive dehalogenation to aryl radicals for chemical transformations ...
Huimin Guo, Xing Guan, Heping Li, Weihua Guo   +3 more
doaj   +1 more source

Crystal Structure of the Apo-Form of NADPH-Dependent Thioredoxin Reductase from a Methane-Producing Archaeon

Antioxidants, 2018
The redox regulation of proteins via reversible dithiol/disulfide exchange reactions involves the thioredoxin system, which is composed of a reductant, a thioredoxin reductase (TR), and thioredoxin (Trx).
Rubén M. Buey, Ruth A. Schmitz, Bob B. Buchanan, Monica Balsera   +3 more
doaj   +1 more source