Results 61 to 70 of about 15,113 (160)
MicroorganismsWe previously reported the first-in-human assessment of three doses (2, 5, and 10 µg) of purified inactivated Zika virus vaccine (PIZV or TAK-426) in the Phase 1 ZIK-101 study (NCT03343626).
Camilo J. Acosta +5 more
doaj +1 more source
Stress in dipteran insects mass‐reared for sterile insect technique applications
Insect Science, EarlyView.The connections between biotic and abiotic stress affecting mass‐reared dipteran insects and the associated stress and immunological responses. Numbers indicate the order in which the topics are discussed in this review. Abstract Stress may be viewed as the disturbance of homeostasis of an organism.
Caroline K. Mirieri +3 more
wiley +1 more source
Infection order outweighs the role of CD4+ T cells in tertiary flavivirus exposure
iScience, 2022 Summary: The link between CD4+ T and B cells during immune responses to DENV and ZIKV and their roles in cross-protection during heterologous infection is an active area of research.
Nicole Marzan-Rivera +13 more
doaj
Recent Advances in the Development of Virus-Like Particle-Based Flavivirus Vaccines
Vaccines, 2020 Flaviviruses include several medically important viruses, such as Zika virus (ZIKV), Dengue virus (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV).
Naru Zhang +3 more
doaj +1 more source
Rational design of West Nile virus vaccine through large replacement of 3′ UTR with internal poly(A)
EMBO Molecular Medicine, 2021 The genus Flavivirus comprises numerous emerging and re‐emerging arboviruses causing human illness. Vaccines are the best approach to prevent flavivirus diseases.
Ya‐Nan Zhang +15 more
doaj +1 more source
Insects, 2021 Arthropod-borne viruses belonging to the flavivirus genus possess an enormous relevance in public health. Neotropical non-human primates (NPs) have been proposed to be susceptible to flavivirus infections due to their arboreal and diurnal habits, their ...
Andrea Chaves +6 more
doaj +1 more source
Spatio‐temporal Usutu virus model explains Eurasian blackbird Turdus merula population trends
Ecography, EarlyView.Emerging vector‐borne pathogens (VBPs) pose significant global health threats, occasionally causing widespread outbreaks with high wildlife mortality. Understanding climatic and anthropogenic drivers behind transmission dynamics in wildlife populations is key to mitigate health risks.
Jurrian Van Irsel +7 more
wiley +1 more source
PLoS Pathogens, 2018 Molecular determinants and mechanisms of arthropod-borne flavivirus transmission to the vertebrate host are poorly understood. In this study, we show for the first time that a cell line from medically important arthropods, such as ticks, secretes ...
Wenshuo Zhou +7 more
semanticscholar +1 more source
Medical and Veterinary Entomology, EarlyView.We identified Culex pipiens bloodmeals at the species level in natural, agricultural and peri‐urban habitats and calculated host preferences based on forage ratios. This analysis showed Passeriformes, and in particular Columba livia, Passer montanus and Turdus sp., to be the preferred Cx. pipiens hosts.
Víctor Rodríguez‐Valencia +9 more
wiley +1 more source
Structural basis for STAT2 suppression by flavivirus NS5
Nature Structural & Molecular Biology, 2020 Suppressing cellular signal transducers of transcription 2 (STAT2) is a common strategy that viruses use to establish infections, yet the detailed mechanism remains elusive, owing to a lack of structural information about the viral–cellular complex ...
Boxiao Wang +16 more
semanticscholar +1 more source