Results 61 to 70 of about 60,474 (247)

Molecular characterization of flaviviruses from field-collected mosquitoes in northwestern Italy, 2011–2012

Parasites & Vectors, 2014
Background The genus Flavivirus comprises several mosquito-borne species, including the zoonotic pathogens West Nile and Usutu virus, circulating in animals and humans in Italy since 1998.
Francesca Rizzo, Francesco Cerutti, Marco Ballardini, Andrea Mosca, Nicoletta Vitale, Maria Cristina Radaelli, Rosanna Desiato, Marino Prearo, Alessandra Pautasso, Cristina Casalone, Pierluigi Acutis, Simone Peletto, Maria Lucia Mandola   +12 more
doaj   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Dimerization of Flavivirus NS4B Protein [PDF]

Journal of Virology, 2014
ABSTRACT Flavivirus replication is mediated by a complex machinery that consists of viral enzymes, nonenzymatic viral proteins, and host factors. Many of the nonenzymatic viral proteins, such as NS4B, are associated with the endoplasmic reticulum membrane.
Dong, Hongping, Reynaud, Aline, Zou, Jing, Xie, Xuping, Lee, Le Tian, Chandrasekaran, Ramya, Yap, Lijian, Wang, Qing-Yin, Kang, Congbao, Yuan, Zhiming, Lescar, Julien, Shi, Pei-Yong   +11 more
openaire   +4 more sources

Detection of Zika and dengue viruses in wild-caught mosquitoes collected during field surveillance in an environmental protection area in São Paulo, Brazil.

PLoS ONE, 2020
Species of the genus Flavivirus are widespread in Brazil and are a major public health concern. The country's largest city, São Paulo, is in a highly urbanized area with a few forest fragments which are commonly used for recreation.
Karolina Morales Barrio-Nuevo, Mariana Sequetin Cunha, Adriana Luchs, Aristides Fernandes, Iray Maria Rocco, Luis Filipe Mucci, Renato Pereira de Souza, Antônio Ralph Medeiros-Sousa, Walter Ceretti-Junior, Mauro Toledo Marrelli   +9 more
doaj   +1 more source

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]

, 2006
In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi, Baumert, Thomas, Chisari, Francis V, Kapadia, Sharookh B, McKeating, Jane A   +4 more
core   +2 more sources

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Flavivirus Susceptibility in Aedes aegypti [PDF]

Archives of Medical Research, 2002
Aedes aegypti is the primary vector of yellow fever (YF) and dengue fever (DF) flaviviruses worldwide. In this review we focus on past and present research on genetic components and environmental factors in Aedes aegypti that appear to control flavivirus transmission. We review genetic relationships among Ae.
Black, William C., Bennett, Kristine E., Gorrochótegui Escalante, Norma, Barillas Mury, Carolina V., Fernández Salas, Ildefonso, Muñoz, María de Lourdes, Farfán Ale, José Arturo, Olson, Ken E., Beaty, Barry J.   +8 more
openaire   +2 more sources

Serosurvey of Nonhuman Primates in Costa Rica at the Human–Wildlife Interface Reveals High Exposure to Flaviviruses

Insects, 2021
Arthropod-borne viruses belonging to the flavivirus genus possess an enormous relevance in public health. Neotropical non-human primates (NPs) have been proposed to be susceptible to flavivirus infections due to their arboreal and diurnal habits, their ...
Andrea Chaves, Martha Piche-Ovares, Carlos N. Ibarra-Cerdeña, Eugenia Corrales-Aguilar, Gerardo Suzán, Andres Moreira-Soto, Gustavo A. Gutiérrez-Espeleta   +6 more
doaj   +1 more source

Mortality associated with avian reovirus infection in a free-living magpie (Pica pica) in Great Britain [PDF]

, 2015
Avian reoviruses (ARVs) cause a range of disease presentations in domestic, captive and free-living bird species. ARVs have been reported as a cause of significant disease and mortality in free-living corvid species in North America and continental ...
Cunningham, AA, Dastjerdi, A, Everest, D, Hicks, D, Horton, DL, Irvine, RM, Lawson, B, Núñez, A, Pocknell, A, Shah, S   +9 more
core   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source