Results 61 to 70 of about 53,374 (257)

In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination. [PDF]

PLoS Neglected Tropical Diseases, 2017
Infection caused by the four serotypes of dengue virus (DENV-1-4) is a leading cause of mosquito-borne disease. Clinically-severe dengue disease is more common when secondary dengue infection occurs following prior infection with a heterologous dengue ...
Stephen S Whitehead, Anna P Durbin, Kristen K Pierce, Dan Elwood, Benjamin D McElvany, Ellen A Fraser, Marya P Carmolli, Cecilia M Tibery, Noreen A Hynes, Matthew Jo, Janece M Lovchik, Catherine J Larsson, Elena A Doty, Dorothy M Dickson, Catherine J Luke, Kanta Subbarao, Sean A Diehl, Beth D Kirkpatrick   +17 more
doaj   +1 more source

A Perspective on Current Flavivirus Vaccine Development: A Brief Review

Viruses, 2023
The flavivirus genus contains several clinically important pathogens that account for tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can cause severe and potentially fatal diseases ranging from hemorrhagic fevers ...
Sudip Kumar Dutta, Thomas Langenburg
doaj   +1 more source

Population, sexual and reproductive health, rights and sustainable development: forging a common agenda. [PDF]

, 2010
This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate ...
Campbell, D. M., Carter, P. E., Collins-Emerson, J. M., French, N. P., Hathaway, S., Marshall, J., Midwinter, A. C., Mullner, P., Pirie, R., Shadbolt, T., Spencer, Simon E. F., Wilson, D. J.   +11 more
core   +1 more source

Flavivirus membrane fusion

Journal of General Virology, 2006
Flavivirus membrane fusion is mediated by a class II viral fusion protein, the major envelope protein E, and the fusion process is extremely fast and efficient. Understanding of the underlying mechanisms has been advanced significantly by the determination of E protein structures in their pre- and post-fusion conformations and by the elucidation of the
Franz X. Heinz, Karin Stiasny
openaire   +3 more sources

Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines

Frontiers in Immunology, 2022
The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan, Yuhong Pan, Yuhong Pan, Wenjun Cai, Wenjun Cai, Wenjun Cai, Anchun Cheng, Anchun Cheng, Anchun Cheng, Mingshu Wang, Mingshu Wang, Mingshu Wang, Zhongqiong Yin, Renyong Jia, Renyong Jia, Renyong Jia   +15 more
doaj   +1 more source

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]

, 2006
In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi, Baumert, Thomas, Chisari, Francis V, Kapadia, Sharookh B, McKeating, Jane A   +4 more
core   +2 more sources

Improved reference genome of the arboviral vector Aedes albopictus [PDF]

, 2020
Background: The Asian tiger mosquito Aedes albopictus is globally expanding and has become the main vector for human arboviruses in Europe. With limited antiviral drugs and vaccines available, vector control is the primary approach to prevent mosquito ...
Akbari, Omar,, Antoshechkin, Igor, Biedler, James,, Bonizzoni, Mariangela, Caccone, Adalgisa, Cosme, Luciano,, Crawford, Jacob,, Failloux, Anna-Bella, Gamez, Stephanie, Ghurye, Jay, Halbach, Rebecca, Jenrette, Jeremy, Johnston, J. Spencer, Karagodin, Dmitry,, Koren, Sergey, Krsticevic, Flavia, Marconcini, Michele, Masri, Reem,, Masterson, Patrick, Miesen, Pascal, Palatini, Umberto, Papathanos, Philippos,, Phillippy, Adam,, Pischedda, Elisa, Powell, Jeffrey, Rhie, Arang, Sharakhova, Maria,, Sharma, Atashi, Thibaud-Nissen, Francoise, Tu, Zhijian, van Rij, Ronald,   +30 more
core   +4 more sources

Flavivirus Entry Receptors: An Update [PDF]

Viruses, 2013
Flaviviruses enter host cells by endocytosis initiated when the virus particles interact with cell surface receptors. The current model suggests that flaviviruses use at least two different sets of molecules for infectious entry: attachment factors that concentrate and/or recruit viruses on the cell surface and primary receptor(s) that bind to virions ...
Laurent Meertens, Xavier Carnec, Ali Amara, Manuel Perera-Lecoin   +3 more
openaire   +4 more sources

Detection of novel insect flavivirus sequences integrated in Aedes albopictus (Diptera: Culicidae) in Northern Italy

Virology Journal, 2009
The presence of DNA sequences integrated from a new flavivirus related to Cell Fusing Agent and Kamiti River Virus was identified in wild Aedes albopictus mosquito populations from the provinces of Trentino and Padova, Northern Italy.
Tenorio Antonio, Seco Mari, Vázquez Ana, Roiz David, Rizzoli Annapaola   +4 more
doaj   +1 more source

Dimerization of Flavivirus NS4B Protein [PDF]

Journal of Virology, 2014
ABSTRACT Flavivirus replication is mediated by a complex machinery that consists of viral enzymes, nonenzymatic viral proteins, and host factors. Many of the nonenzymatic viral proteins, such as NS4B, are associated with the endoplasmic reticulum membrane.
Zhiming Yuan, Pei Yong Shi, Le Tian Lee, Le Tian Lee, Jing Zou, Jing Zou, Ramya Chandrasekaran, Aline Reynaud, Qing Yin Wang, CongBao Kang, Lijian Yap, Xuping Xie, Julien Lescar, Hongping Dong   +13 more
openaire   +4 more sources