Results 71 to 80 of about 59,356 (219)

Impact of flavivirus vaccine-induced immunity on primary Zika virus antibody response in humans.

PLoS Neglected Tropical Diseases, 2020
BackgroundZika virus has recently spread to South- and Central America, causing congenital birth defects and neurological complications. Many people at risk are flavivirus pre-immune due to prior infections with other flaviviruses (e.g.
Stefan Malafa, Iris Medits, Judith H Aberle, Stephan W Aberle, Denise Haslwanter, Georgios Tsouchnikas, Silke Wölfel, Kristina L Huber, Elena Percivalle, Pascal Cherpillod, Melissa Thaler, Lena Roßbacher, Michael Kundi, Franz X Heinz, Karin Stiasny   +14 more
doaj   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, EarlyView.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Dengue and Zika virus cross-reactive human monoclonal antibodies protect against Spondweni virus infection and pathogenesis in mice [PDF]

, 2019
Summary: Spondweni virus (SPOV) is the flavivirus that is most closely related to Zika virus (ZIKV). Although SPOV causes sporadic human infections in Africa, recently it was found in Culex mosquitoes in Haiti.
Aliota, Ansarah-Sobrinho, Barba-Spaeth, Cerbino-Neto, Cugola, Culshaw, Dejnirattisai, Dejnirattisai, Dowd, Draper, Driggers, Elong Ngono, Falk, Fernandez, Fox, Goncé, Gorman, Govero, Grant, Haddow, Haddow, Halstead, Hasan, Hessell, Jagger, Kokernot, Lanciotti, Lazear, Ma, MacNamara, Mansuy, Mansuy, Mansuy, McDonald, Miner, Morrison, Morrison, Mukherjee, Nguyen, Oliphant, Pal, Pierson, Pierson, Platt, Richner, Rossi, Rouvinski, Sapparapu, Sheehan, Suy, Taraphdar, White, Zhao   +52 more
core   +3 more sources

Immunological and Safety Considerations When Selecting the Dose Formulation of a Purified Inactivated Zika Virus Vaccine (PIZV)

Microorganisms
We previously reported the first-in-human assessment of three doses (2, 5, and 10 µg) of purified inactivated Zika virus vaccine (PIZV or TAK-426) in the Phase 1 ZIK-101 study (NCT03343626).
Camilo J. Acosta, Francesco Nordio, Eloi Kpamegan, Kelley J. Moss, Pradeep Kumar, Kazuhiro Hirata   +5 more
doaj   +1 more source

Triage and care for women with symptoms or diagnosis of pregnancy loss between 14 + 0 and 21 + 6 weeks' gestation

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Mid‐trimester pregnancy loss (MTL), defined as a pregnancy loss occurring between 14 + 0 and 21 + 6 weeks of gestation, causes significant physical and emotional distress to women and presents clinical challenges to healthcare professionals. It is acknowledged that in low‐resource settings, this guideline might be applicable to births up to 28 
Caroline E. Fox, Rosinder Kaur, Kugajeevan Vigneswaran, Rachel Small, Jenny Carter, Keelin O'Donoghue, Alexander E. P. Heazell, Anna L. David, Nigel Simpson, Angharad Care, Lisa Starrs, Andrew Shennan, Catalina María Valencia González, Priya Soma‐Pillay, Leah Fitzsimmons, Adam J. Devall, Arri Coomarasamy, Mid‐trimester Pregnancy Loss Guideline Consensus Panel, Owen Arthurs, Ruth Bender‐Atik, Phil Bennett, Kirstien Boelaert, Elizabeth Bonney, Leanna Brace, Naomi Carlisle, Davide Casagrandi, Manju Chandiramani, Carolyn Chiswick, Alexandra Emms, Stella Fielder, James Goadsby, Laura Goodfellow, Jim Gray, Jemma Johns, Emma Kirk, Will Lester, Sophie Mackay, Maria Memtsa, Katie Morris, Sunbal Mukhtar, Naimah Raza, Rita Sarquis, Neil Sebire, Lucy Smith, Lucy Spencer, Amos Tetteh, Natalie Woodhead   +46 more
wiley   +1 more source

Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses [PDF]

, 2017
The Flavivirus genus (Flaviviridae family) contains a number of important human pathogens, including dengue and Zika viruses, which have the potential to cause severe disease.
Clark, Jordan J., Cumberworth, Stephanie, Donald, Claire L., Kohl, Alain   +3 more
core   +1 more source

GISDD: A comprehensive global integrated sequence and genotyping database platform for dengue virus, facilitating a stratified coordinated surveillance strategy

iMetaOmics, EarlyView.
GISDD, the Global Integrated Sequence and Genotyping Database for Dengue Virus (DENV), provides an integrated online analysis platform encompassing tools such as GISDDrlearn, GISDDprimer, and GISDDref, enabling swift identification and tracing of well‐established DENV genotypes, subgenotypes, and clades, thereby facilitating a stratified global ...
Xiang Guo, Pingying Teng, Ziyao Li, Liqiang Li, Xiaohua Liu, Xiaoqing Zhang, Yuji Wang, Minling Hu, Wenwen Ren, Shu Zeng, Haiyang Chen, Liu Ge, Shihan Liu, Zhiqiang Peng, Jiufeng Sun, Xin Zhang, Lei Luo, Jie Peng, Benyun Shi, Rangke Wu, Jiming Liu, Fuchun Zhang, Xiao‐Guang Chen, Tong Chen, Xiaohong Zhou   +24 more
wiley   +1 more source

A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation [PDF]

, 2019
Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme ...
Chaminda, Gunawardene D., Newburn, Laura R., White, K. Andrew   +2 more
core   +1 more source

Búsqueda de flavivirus en individuos con sospecha clínica de dengue y resultado negativo para el antígeno NS1 en Paraguay

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2017
Los flavivirus son responsables de una considerable morbi-mortalidad a nivel mundial. Entre ellos, el virus del dengue (DENV) es causante de graves problemas de salud pública en Paraguay.
Fátima María Cardozo Segovia, Alejandra María Rojas Segovia, Leticia Franco, Lilian Herebia, María Asunción Vallejos, Gloria Malvina Páez Acchiardi, Yvalena Guillén, Laura Patricia Mendoza Torres   +7 more
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