Results 81 to 90 of about 59,356 (219)

ZIKV Phylogenetic Characterization Reveals Evolutionary Diversity, Regional Dissemination, and Emergence of African Lineages in Brazil

Journal of Basic Microbiology, EarlyView.
ABSTRACT During the last epidemic in 2015–2016, Zika virus (ZIKV) gaining worldwide attention due to its association with neurological complications such as microcephaly and Guillain‐Barré syndrome. ZIKV can be transmitted through vector‐borne, sexual, maternal‐fetal, and blood transfusion transmission.
Thayane da Encarnação Sá‐Guimarães, Pedro Panzenhagen, Anita Ferreira do Valle, Carlos Adam Conte Junior, Mônica Ferreira Moreira   +4 more
wiley   +1 more source

Seroprevalence of Zika virus in wild African green monkeys and baboons [PDF]

, 2017
Zika virus (ZIKV) has recently spread through the Americas and has been associated with a range of health effects, including birth defects in children born to women infected during pregnancy. Although the natural reservoir of ZIKV remains poorly defined,
Adam L. Bailey, Andrea M. Weiler, Anna J. Jasinska, Clifford J. Jolly, Connor R. Buechler, Cristian Apetrei, David H. O’Connor, Gabrielle L. Barry, Jane E. Phillips-Conroy, Jeffrey Rogers, John Schoggins, Laurel M. Stewart, Meghan E. Breitbach, Nelson B. Freimer, Thomas C. Friedrich   +14 more
core   +3 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Determinants of the population growth of the West Nile virus mosquito vector Culex pipiens in a repeatedly affected area in Italy [PDF]

, 2014
Background The recent spread of West Nile Virus in temperate countries has raised concern. Predicting the likelihood of transmission is crucial to ascertain the threat to Public and Veterinary Health.
Bonfanti, L., Capelli, G., Ferguson, H.M., Marangon, S., Montarsi, F., Mulatti, P.   +5 more
core   +1 more source

Toll-Like Receptors and RIG-I-Like Receptors Play Important Roles in Resisting Flavivirus

Journal of Immunology Research, 2018
Flaviviridae family is a class of single-stranded RNA virus, which is fatal to human and animals and mainly prevalent in subtropic and tropic countries.
Hong-Yan Guo, Xing-Cui Zhang, Ren-Yong Jia   +2 more
doaj   +1 more source

Crystal structure of the NS3-like helicase from Alongshan virus

IUCrJ, 2020
Alongshan virus (ALSV) is an emerging human pathogen that was identified in China and rapidly spread to the European continent in 2019, raising concerns about public health.
Xiaopan Gao, Kaixiang Zhu, Justyna Aleksandra Wojdyla, Pu Chen, Bo Qin, Ziheng Li, Meitian Wang, Sheng Cui   +7 more
doaj   +1 more source

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

Nano Select, EarlyView.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis [PDF]

, 2016
The interferon-induced transmembrane protein (IFITM) family of proteins inhibit infection of several different enveloped viruses in cell culture by virtue of their ability to restrict entry and fusion from late endosomes.
Bradbury LE, Chen YX, Ebel GD, Evans SS, Frey M, Omalu BI, Takahashi S   +6 more
core   +2 more sources

Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch, Reinhard Albrecht, Ebbe S. Andersen, Hsuan‐Ai Chen, Wah Chiu, Rhiju Das, Jeanine G. Gezelle, Marcus D. Hartmann, Claudia Höbartner, Yimin Hu, Shekhar Jadhav, Philip E. Johnson, Christopher P. Jones, Deepak Koirala, Emil L. Kristoffersen, Eric Largy, Anna Lewicka, Cameron D. Mackereth, Marco Marcia, Michela Nigro, Manju Ojha, Joseph A. Piccirilli, Phoebe A. Rice, Heewhan Shin, Anna‐Lena Steckelberg, Zhaoming Su, Yoshita Srivastava, Liu Wang, Yuan Wu, Jiahao Xie, Nikolaj H. Zwergius, John Moult, Andriy Kryshtafovych   +32 more
wiley   +1 more source

The glycosylation deficiency of flavivirus NS1 attenuates virus replication through interfering with the formation of viral replication compartments

Journal of Biomedical Science
Background Flavivirus is a challenge all over the world. The replication of flavivirus takes place within membranous replication compartments (RCs) derived from endoplasmic reticulum (ER).
Shuhan Huang, Pan-Deng Shi, Xiao-Xuan Fan, Yang Yang, Cheng-Feng Qin, Hui Zhao, Lei Shi, Yali Ci   +7 more
doaj   +1 more source