Results 81 to 90 of about 68,853 (304)
Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells
Frontiers in Immunology, 2019 Most of the world is at risk of being infected with a flavivirus such as dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus, significantly impacting millions of lives. Importantly,
Mariah Hassert +2 more
doaj +1 more source
Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines
Frontiers in Immunology, 2022 The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan +15 more
doaj +1 more source
Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]
, 2006 In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi +4 more
core +2 more sources
Improved reference genome of the arboviral vector Aedes albopictus [PDF]
, 2020 Background: The Asian tiger mosquito Aedes albopictus is globally expanding and has become the main vector for human arboviruses in Europe. With limited antiviral drugs and vaccines available, vector control is the primary approach to prevent mosquito ...
Akbari, Omar, +30 more
core +4 more sources
Virology Journal, 2009 The presence of DNA sequences integrated from a new flavivirus related to Cell Fusing Agent and Kamiti River Virus was identified in wild Aedes albopictus mosquito populations from the provinces of Trentino and Padova, Northern Italy.
Tenorio Antonio +4 more
doaj +1 more source
Flavivirus Entry Receptors: An Update [PDF]
Viruses, 2013 Flaviviruses enter host cells by endocytosis initiated when the virus particles interact with cell surface receptors. The current model suggests that flaviviruses use at least two different sets of molecules for infectious entry: attachment factors that concentrate and/or recruit viruses on the cell surface and primary receptor(s) that bind to virions ...
Laurent Meertens +3 more
openaire +4 more sources
Parasites & Vectors, 2014 Background The genus Flavivirus comprises several mosquito-borne species, including the zoonotic pathogens West Nile and Usutu virus, circulating in animals and humans in Italy since 1998.
Francesca Rizzo +12 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Dimerization of Flavivirus NS4B Protein [PDF]
Journal of Virology, 2014 ABSTRACT Flavivirus replication is mediated by a complex machinery that consists of viral enzymes, nonenzymatic viral proteins, and host factors. Many of the nonenzymatic viral proteins, such as NS4B, are associated with the endoplasmic reticulum membrane.
Zhiming Yuan +13 more
openaire +4 more sources
Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]
, 2015 Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...
core +1 more source