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Flaviviruses in AntiTumor Therapy [PDF]
Oncolytic viruses offer a promising approach to tumor treatment. These viruses not only have a direct lytic effect on tumor cells but can also modify the tumor microenvironment and activate antitumor immunity. Due to their high pathogenicity, flaviviruses have often been overlooked as potential antitumor agents.
Alina S. Nazarenko +7 more
openalex +4 more sources
Yellow fever virus (YFV) caused an outbreak in the Brazilian Southeast from 2016 to 2019, of the most significant magnitude since the 1900s. An investigation of the circulating virus revealed that most of the genomes detected in this period carried nine ...
Nathália Dias Furtado +4 more
doaj +1 more source
Mechanisms of Neuroinvasion and Neuropathogenesis by Pathologic Flaviviruses
Flaviviruses are present on every continent and cause significant morbidity and mortality. In many instances, severe cases of infection with flaviviruses involve the invasion of and damage to the central nervous system (CNS). Currently, there are several
Liset de Vries, Alfred T. Harding
semanticscholar +1 more source
Serological cross-reactivity among common flaviviruses
The Flavivirus genus is made up of viruses that are either mosquito-borne or tick-borne and other viruses transmitted by unknown vectors. Flaviviruses present a significant threat to global health and infect up to 400 million of people annually.
Kai Rol Chan +6 more
semanticscholar +1 more source
Horses as Sentinels for the Circulation of Flaviviruses in Eastern–Central Germany
Since 2018, autochthonous West Nile virus (WNV) infections have been regularly reported in eastern–central Germany. While clinically apparent infections in humans and horses are not frequent, seroprevalence studies in horses may allow the tracing of WNV ...
Leonard M R Gothe +9 more
semanticscholar +1 more source
Causes of Phenotypic Variability and Disabilities after Prenatal Viral Infections
Prenatal viral infection can lead to a spectrum of neurodevelopmental disabilities or fetal demise. These can include microencephaly, global developmental delay, intellectual disability, refractory epilepsy, deafness, retinal defects, and cortical-visual
Youssef A. Kousa, Reafa A. Hossain
doaj +1 more source
Arthropod-Borne Flaviviruses in Pregnancy
Flaviviruses are a diverse group of enveloped RNA viruses that cause significant clinical manifestations in the pregnancy and postpartum periods. This review highlights the epidemiology, pathophysiology, clinical features, diagnosis, and prevention of ...
A. Howard-Jones +6 more
semanticscholar +1 more source
Metabolic response to CNS infection with flaviviruses
Flaviviruses are arthropod-borne RNA viruses found worldwide that, when introduced into the human body, cause diseases, including neuroinfections, that can lead to serious metabolic consequences and even death. Some of the diseases caused by flaviviruses
Marta Dobrzyńska +2 more
semanticscholar +1 more source
Tetraspanins as Potential Therapeutic Candidates for Targeting Flaviviruses
Tetraspanin family of proteins participates in numerous fundamental signaling pathways involved in viral transmission, virus-specific immunity, and virus-mediated vesicular trafficking.
Waqas Ahmed +4 more
doaj +1 more source
Mosquito-Borne Flaviviruses and Current Therapeutic Advances
Mosquito-borne flavivirus infections affect approximately 400 million people worldwide each year and are global threats to public health. The common diseases caused by such flaviviruses include West Nile, yellow fever, dengue, Zika infection and Japanese
X. Qian, Zhongtian Qi
semanticscholar +1 more source

