Results 181 to 190 of about 52,238 (309)

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Phenolic Content, Antioxidant Activity, Phytochemical Diversity, and Toxicological Potential of Tetradenia riparia (Hochst.) Codd Leaves

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
ABSTRACT Tetradenia riparia (Hochst.) Codd is a medicinal plant widely used in traditional medicine. However, comprehensive studies integrating its chemical composition, antioxidant capacity, and toxicological safety are still limited. This study aimed to characterize the phenolic content, antioxidant activity, phytochemical diversity, and ...
Caroline dos Santos Giuliani, Carla Andressa Almeida Farias, Patrícia Kolling Marquezan, Karoline Longo de Aguiar, Elize Musachio, Andreara Rodrigues dos Reis, Nathália Cardoso de Afonso Bonotto, Fernanda Barbisan, Milene Teixeira Barcia, Ana Lúcia Souza Silva Mateus, Aline Sobreira Bezerra, José Laerte Nörnberg   +11 more
wiley   +1 more source

Antioxidant and selective cytotoxic activity of Dipterocarpus obtusifolius flower extract against gastrointestinal cancer, with bioactive component profiling. [PDF]

BMC Complement Med Ther
Luechine A, Techasen A, Phetcharaburanin J, Ditcharoen S, Loilome W, Armartmuntree N, Thanee K, Promraksa B, Anantaworasakul P, Thanee M.   +9 more
europepmc   +1 more source

Mapping the Technological and Pharmacological Landscape of Casearia sylvestris: An Evidence‐Based Prospection for Wound Healing and Pain Management

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Technological prospection of Casearia sylvestris for wound healing reveals limited patent and scientific production, concentrated on topical formulations and associated analgesic and anti‐inflammatory properties. Key innovation gaps persist, including insufficient chemical and biological standardization, lack of clinical evidence, and restricted ...
Luiza Gonçalves Soutier, Yasmim Parisotto de Souza Silva, Carla Suelen Gurski, Jaqueline Carneiro, Jéssica Brandão Reolon, Roberto Pontarolo, Marcel Henrique Marcondes Sari, Gabriel Blum Vestena, Weber Cláudio Francisco Nunes da Silva, Juliana Sartori Bonini, Luana Mota Ferreira   +10 more
wiley   +1 more source

Comprehensive Phytochemical and Biological Evaluation of <i>Boerhavia elegans</i> Extracts: Anticancer and Antioxidant Activities in Various Solvent Systems. [PDF]

Int J Anal Chem
Al-Raddadi TM, Bahaffi SO, Alkhateeb LA, Kalantan AA, Adam AM, Zughaibi T, Ali EMM.   +6 more
europepmc   +1 more source

Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis

ChemistryEurope, Volume 4, Issue 5, May 2026.
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley   +1 more source

Metabolite Profiling and Anticancer Evaluation of Iraqi Haloxylon articulatum Halophyte via LC-HRMS/MS, Molecular Docking, and ADMET Analysis. [PDF]

Chem Biodivers
Abidi J, Hassena AB, Hmida RB, Kulinowski Ł, Aytar EC, Al-Rashidi RR, Bouaziz M.   +6 more
europepmc   +1 more source

Mechanochemically Driven Synthesis of Anticancer Cocrystals: A Case Study of Lenalidomide

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The combination of crystal engineering and mechanochemical approaches is a powerful strategy for the rational screen and development of new solid forms of active pharmaceutical ingredients (API). New supramolecular patterns formed between an API and a coformer allow the adjustment of physicochemical properties of drugs.
Ana C. S. Carvalho, M. Teresa Duarte, Clara S. B. Gomes, Mafalda Sarraguça, Alessia Bacchi, Michele Prencipe, Job Gieling, Natalia Shemchuk, Daniel M. Baier, Koen Robeyns, Hector Polyzois, Lidia Tajber, Christos M. Chatzigiannis, Evelina Colacino, Tom Leyssens, Vânia André   +15 more
wiley   +1 more source

<i>In vitro</i> bioactivity and phytochemical characterization of a polyherbal extract with antioxidant and anticancer properties. [PDF]

PeerJ
Ammari AA, Aljawdah HM, Amran RA, Alhimaidi AR.   +3 more
europepmc   +1 more source

Noni (Morinda citrifolia L.) Fermented Juice Inhibits Tumor Progression of Breast Cancer Angiogenesis Through Suppressing NF‐κB Signaling

Food Frontiers, Volume 7, Issue 3, May 2026.
Noni fermented juice (NFJ) suppresses breast cancer progression by inhibiting angiogenesis via the Ikkβ/NF‐κB/VEGF pathway. This study demonstrates the potent antitumor effects of NFJ through the inhibition on the function of endothelial cells, identifying it as a safe therapeutic agent for breast cancer treatment. ABSTRACT Angiogenesis plays a crucial
Baijian Wu, Xiaoyu Xu, Zhihong Zhu, Yau‐Tuen Chan, Shaozhong Peng, Yanping Liu, Cheng Zhang, Ming Zhou, Xiaodan Huang, Yibin Feng   +9 more
wiley   +1 more source