Results 81 to 90 of about 513,313 (409)

Current understanding of the pathways of flavonoid biosynthesis in model and crop plants.

open access: yesJournal of Experimental Botany, 2017
Flavonoids are a signature class of secondary metabolites formed from a relatively simple collection of scaffolds. They are extensively decorated by chemical reactions including glycosylation, methylation, and acylation.
Takayuki Tohge   +2 more
semanticscholar   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao   +8 more
wiley   +1 more source

Plant Flavonoid Production in Bacteria and Yeasts

open access: yesFrontiers in Chemical Engineering, 2022
Flavonoids, a major group of secondary metabolites in plants, are promising for use as pharmaceuticals and food supplements due to their health-promoting biological activities. Industrial flavonoid production primarily depends on isolation from plants or
Shota Isogai   +11 more
doaj   +1 more source

How to perform RT-qPCR accurately in plant species?: a case study on flower colour gene expression in an azalea (Rhododendron simsii hybrids) mapping population [PDF]

open access: yes, 2013
Background: Flower colour variation is one of the most crucial selection criteria in the breeding of a flowering pot plant, as is also the case for azalea (Rhododendron simsii hybrids).
De Keyser, Ellen   +3 more
core   +2 more sources

Flavonoids as Anticancer Agents [PDF]

open access: yesNutrients, 2020
Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids, flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants. Fruits, vegetables, plant-derived beverages such as green tea, wine and cocoa-based products are the main dietary sources of flavonoids.
Dalia M. Kopustinskiene   +3 more
openaire   +2 more sources

Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening

open access: yesAdvanced Materials Technologies, EarlyView.
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló   +5 more
wiley   +1 more source

Synthesis of activity evaluation of flavonoid derivatives as ɑ-glucosidase inhibitors

open access: yesFrontiers in Chemistry, 2022
Six flavonoid derivatives were synthesized and tested for anti-α-glucosidase activities. All derivatives were confirmed using NMR and HRMS and exhibited excellent inhibitory effects on α-glucosidase.
Hua Zhu, Xin Zhong
doaj   +1 more source

A SQUAMOSA MADS-box gene involved in the regulation of anthocyanin accumulation in bilberry fruits [PDF]

open access: yes, 2010
Anthocyanins are important health promoting phytochemicals that are abundant in many fleshy fruits. Bilberry (Vaccinium myrtillus L.) is one of the best sources of these compounds.
Fraser, Paul D.   +11 more
core   +5 more sources

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

open access: yesAdvanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı   +7 more
wiley   +1 more source

Ethanol-ammonium Sulfate Aqueous Two-phase Extraction of Total Flavonoids from Peach Blossom and Its Antioxidant Activity

open access: yesShipin gongye ke-ji, 2022
The extraction technology of total flavonoids from peach blossom was studied by theaqueous two-phase system of ethanol and ammonium sulfate. On the basis of single factor experiments, response surface methodology was used to optimize the extraction ...
Yaowen YU   +4 more
doaj   +1 more source

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