Evaluation of Peppermint Leaf Flavonoids as SARS-CoV-2 Spike Receptor-Binding Domain Attachment Inhibitors to the Human ACE2 Receptor: A Molecular Docking Study [PDF]
Virtual screening is a computational technique widely used for identifying small molecules which are most likely to bind to a protein target. Here, we performed a molecular docking study to propose potential candidates to prevent the RBD/ACE2 attachment. These candidates are sixteen different flavonoids present in the peppermint leaf.
arxiv
Agricultural quality matrix-based multiomics structural analysis of carrots in soils fertilized with thermophile-fermented compost [PDF]
Compost is used worldwide as a soil conditioner for crops, but its functions have still been explored. Here, the omics profiles of carrots were investigated, as a root vegetable plant model, in a field amended with compost fermented with thermophilic Bacillaceae for growth and quality indices.
arxiv +1 more source
Phytochemical study and evaluation of the cytotoxic properties of methanolic extract from Baccharis obtusifolia [PDF]
Some species of the Baccharis genus have been shown to possess important biomedical properties, including cytotoxic activity. In this study, we examined the cytotoxic effect of methanol extract from Baccharis obtusifolia (Asteraceae) in cancer cell lines of prostate (PC-3), colon (RKO), astrocytoma (D-384), and breast (MCF-7).
arxiv +1 more source
A quest for staunch effects of flavonoids: Utopian protection against hepatic ailments
The role of flavonoids as the major red, blue and purple pigments in plants has gained these secondary products a great deal of attention over the years. Flavonoids are polyphenols and occur as aglycones, glycosides and methylated derivatives. Flavonoids
Anju Dhiman, Arun Nanda, Sayeed Ahmad
doaj +1 more source
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang+6 more
wiley +1 more source
Dietary flavonoids of Spanish youth: intakes, sources, and association with the Mediterranean diet [PDF]
Background Plant-based diets have been linked to high diet quality and reduced risk of cardiovascular diseases. The health impact of plant-based diets might be partially explained by the concomitant intake of flavonoids.
Rowaedh Ahmed Bawaked+7 more
doaj +2 more sources
Nutritional composition and bioactive compounds of mini watermelon genotypes in Bangladesh [PDF]
Given the present rising trends in changing lifestyle and consumption patterns, watermelon production has shifted from big to small-sized fruits having desirable quality attributes. Hence, analyses of fruit quality traits of mini watermelon are crucial to develop improved cultivars with enhanced nutritional compositions, consumer-preferred traits and ...
arxiv
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua+5 more
wiley +1 more source
High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Qiang Zeng+9 more
wiley +1 more source
Bioavailability and Metabolism of Flavonoids: A Review [PDF]
Flavonoids are a group of plant antioxidants that are widely distributed in plants from the root and stem to the leaves, flowers, and fruits. They are generally present as glycosides, conjugated to sugars, although their aglycone forms may also exist ...
Masoumeh Akhlaghi, Sahar Foshati
doaj +1 more source