Results 121 to 130 of about 25,623 (248)
Circular inference in visual cortical hierarchies in schizophrenia
Aim In schizophrenia, disrupted perceptual processes contribute to positive symptoms. However, it remains unclear how top‐down priors and bottom‐up likelihoods are represented across the hierarchy of visual cortices. To identify these processes within cortical hierarchies, the circular inference model offers a framework to account for the biased ...
Shuhei Hara +7 more
wiley +1 more source
POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley +1 more source
ABSTRACT Circulating tumor DNA (ctDNA) serves as a non‐invasive liquid biopsy technique, offering potential utility in the prognostic evaluation of multiple myeloma (MM). In this study, we performed a systematic review and updated meta‐analysis to analyze the association between ctDNA and the prognosis of patients diagnosed with MM.
Wanting Ying +3 more
wiley +1 more source
Coumarin‐Based Antifungal Leads: Design, Synthesis, Mechanistic Insights, and Synergistic Activity
A series of novel coumarin derivatives are designed and synthesized as antifungal leads. The optimized compound IVd displays potent activity against plant pathogens, potential multitarget antifungal effects, and synergistic interactions with commercial fungicides, providing a promising strategy for resistance management.
Xiangna Chang +3 more
wiley +1 more source
ABSTRACT Introduction Multiple myeloma is the second most common malignancy of the lymphoid system and accounts for about 2% of cancer deaths. Treatment generally consists of chemotherapy and autologous stem cell transplantation. Clinical trial results are equivocal as to whether autologous stem cell transplantation in the treatment of multiple myeloma
Gurmukh Singh, Kiana Kim, Roni J. Bollag
wiley +1 more source
JMJ18 binds FLC chromatin and mediates the level of H3K4 methylation in FLC chromatin.
(A) Schematic genomic structure of the FLC locus, and the probes used to measure the histone methylation level. Open boxes represent introns, while filled boxes represent exons. B1–B14 indicate the FLC regions recognized by the probes during the analysis
Huixian Mo (170178) +13 more
core +1 more source
ABSTRACT Objective To evaluate the effects of antimicrobial photodynamic therapy (aPDT), systemic pharmacological therapy, and their combination on irradiated mandibular post‐extraction bone repair relevant to osteoradionecrosis (ORN) development in a rat model. Methods Twenty‐six male Wistar rats were initially randomized into five experimental groups:
Larissa Lopes Fonseca +9 more
wiley +1 more source
Power System Stabilizer Driven by an Adaptive Fuzzy Set for Better Dynamic Performance
This paper presents a novel application of a fuzzy logic controller (FLC) driven by an adaptive fuzzy set (AFS) for a power system stabilizer (PSS).The proposed FLC, driven by AFS, is compared with a classical FLC, driven by a fixed fuzzy set (FFS). Both
H. F. Soliman +3 more
doaj
Fluconazole (FLC) is extensively employed for the prophylaxis and treatment of invasive fungal infections (IFIs). However, the fungistatic nature of FLC renders pathogenic fungi capable of developing tolerance towards it.
Wanqian Li +6 more
doaj +1 more source
Polyphenism Through RNA Chemical Modifications
ABSTRACT Polyphenism, the capacity of a single genotype to produce discrete phenotypes in response to environmental cues, has long served as a model for understanding developmental plasticity. While classical studies have highlighted hormonal signalling and transcription‐factor‐driven gene regulatory networks that mediate these environmentally induced ...
Ralf Schneider, Ehsan Pashay Ahi
wiley +1 more source

