Results 41 to 50 of about 677,770 (306)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Impulse Moments Influence on Single-Frequency Torsional Oscillations of Nonlinear Flexible Bodies
The method of analytical study of the influence of impulse moments on nonlinear torsional oscillations of a homogeneous constant cross-section of a body under classical boundary conditions of the first, second, and third types have been developed.
Mariia Sokil +4 more
doaj +1 more source
RIBFIND: a web server for identifying rigid bodies in protein structures and to aid flexible fitting into cryo EM maps [PDF]
Motivation: To better analyze low-resolution cryo electron microscopy maps of macromolecular assemblies, component atomic structures frequently have to be flexibly fitted into them.
A. P. Pandurangan +12 more
core +1 more source
Precision control for a flexible body representation
Adaptive body representation requires the continuous integration of multisensory inputs within a flexible 'body model' in the brain. The present review evaluates the idea that this flexibility is augmented by the contextual modulation of sensory processing 'top-down'; which can be described as precision control within predictive coding formulations of ...
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Research on Dynamic Performance of Wheel-Rail Contact Under Multiple Flexible Factors
In order to improve the calculation accuracy of the vibration response of vehicle system, based on the rigid flexible coupling dynamics theory, the wheelset, frame and track were considered as flexible bodies, and the vehicle track coupling dynamics ...
Peng YUE +3 more
doaj
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Internally supported flexible duct joint [PDF]
An internally supported, flexible duct joint for use in conducting fluids under relatively high pressures in systems where relatively large deflection angles must be accommodated is presented.
Kuhn, R. F., Jr.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
We report herein on two cases where high-risk osseous foreign bodies that incarcerated or penetrated the bronchial wall. The foreign bodies were unable to be removed via flexible bronchoscope (FB), with the foreign bodies close to the pulmonary artery ...
Haidong Huang +22 more
doaj +1 more source

