Results 61 to 70 of about 681,599 (308)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
eLife, 2018 Macromolecular complexes that exhibit continuous forms of structural flexibility pose a challenge for many existing tools in cryo-EM single-particle analysis. We describe a new tool, called multi-body refinement, which models flexible complexes as a user-
Takanori Nakane +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
MBD analysis of flexible multibody system with mass loss
Nihon Kikai Gakkai ronbunshu, 2016 In this paper, we propose a formulation method for flexible multi-body systems with mass loss. The method derives the equation of motion using the velocity transformation method, in consideration of the shift of center-of-mass.
Kanjuro MAKIHARA +2 more
doaj +1 more source
Fire blocking systems for aircraft seat cushions [PDF]
, 1984 A configuration and method for reducing the flammability of bodies of organic materials that thermally decompose to give flammable gases comprises covering the body with a flexible matrix that catalytically cracks the flammable gases to less flammable ...
Kourtides, D. A., Parker, J. A.
core +1 more source
Combining active structural damping and active suspension control in flexible bodied railway vehicles [PDF]
, 2016 There is a desire to design lightweight railway vehicle bodies for future high speed trains. Previously, suppression of structural vibration of the flexible lightweight vehicle body was attempted via use of active suspensions (conventional actuators) or ...
Goodall, Roger +2 more
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Mathematical and Computer Modelling of Dynamical SystemsIn order to obtain the dynamic stress response of the drum and main shaft of a friction hoist under dynamic loads, a dynamic stress calculation model for the friction hoist was constructed based on the flexible multibody modelling method.
Kai Xu, Ying Xiao, Yi Liu
doaj +1 more source
Energy indicators of working bodies for tillage of steam fields in summer [PDF]
BIO Web of ConferencesCurrently, one of the most important stages in obtaining high yields of the main crops is tillage of steam fields in summer. The article considers various variants of working bodies for tillage of steam fields to establish the energy indicators of the ...
Kambulov Sergey +4 more
doaj +1 more source
Inviscid Simulations of Interacting Flags and Falling Sheets
, 2009 We present a fluid dynamics video showing simulations of flexible bodies flapping and falling in an inviscid fluid. Vortex sheets are shed from the trailing edges of the bodies according to the Kutta condition.
Alben, Silas
core