Results 41 to 50 of about 72,796 (265)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Research on Dynamic Performance of Wheel-Rail Contact Under Multiple Flexible Factors

open access: yes机车电传动, 2021
In order to improve the calculation accuracy of the vibration response of vehicle system, based on the rigid flexible coupling dynamics theory, the wheelset, frame and track were considered as flexible bodies, and the vehicle track coupling dynamics ...
Peng YUE   +3 more
doaj  

Flexibility in Hexapod Robots: Exploring Mobility of the Body

open access: yesIEEE Access, 2023
Introducing Myrmex, a hexapod robot designed for autonomous locomotion on unstructured terrains. It was developed a whole-body kinematics model that enables both open-chain and closed-chain control of the robot. This model enhances the flexibility and mobility of the robot.
Rafael P. Bachega   +3 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Endobronchial removal of the high-risk osseous foreign bodies with evaluation and planning by virtual navigation system

open access: yesRespiratory Medicine Case Reports, 2019
We report herein on two cases where high-risk osseous foreign bodies that incarcerated or penetrated the bronchial wall. The foreign bodies were unable to be removed via flexible bronchoscope (FB), with the foreign bodies close to the pulmonary artery ...
Haidong Huang   +22 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Removal of tracheobronchial foreign bodies using flexible and rigid bronchoscopy

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2012
Background: Foreign body inhalation is one of the life threatening emergencies. It may happen at any age, however, most of these accidents occur in children especially below the age of five. Methods: This prospective study was done at Department of chest
Ahmed Youssef Shaaban Gad   +1 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Red muscle activity in bluegill sunfish Lepomis macrochirus during forward accelerations

open access: yesScientific Reports, 2019
Fishes generate force to swim by activating muscles on either side of their flexible bodies. To accelerate, they must produce higher muscle forces, which leads to higher reaction forces back on their bodies from the environment.
Margot A. B. Schwalbe   +3 more
doaj   +1 more source

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