Results 41 to 50 of about 681,599 (308)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Impulse Moments Influence on Single-Frequency Torsional Oscillations of Nonlinear Flexible Bodies
IEEE Access, 2022 The method of analytical study of the influence of impulse moments on nonlinear torsional oscillations of a homogeneous constant cross-section of a body under classical boundary conditions of the first, second, and third types have been developed.
Mariia Sokil +4 more
doaj +1 more source
Precision control for a flexible body representation
Neuroscience & Biobehavioral Reviews, 2022 Adaptive body representation requires the continuous integration of multisensory inputs within a flexible 'body model' in the brain. The present review evaluates the idea that this flexibility is augmented by the contextual modulation of sensory processing 'top-down'; which can be described as precision control within predictive coding formulations of ...
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Research on Dynamic Performance of Wheel-Rail Contact Under Multiple Flexible Factors
机车电传动, 2021 In order to improve the calculation accuracy of the vibration response of vehicle system, based on the rigid flexible coupling dynamics theory, the wheelset, frame and track were considered as flexible bodies, and the vehicle track coupling dynamics ...
Peng YUE +3 more
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Active control of space structures: Proof of concept experiment [PDF]
, 1982 Modern control theory easily works with multiple input/multiple output systems. Two types of systems which fall into this category are flexible systems, where many measurements and several actuators are necessary to provide control over bending behavior,
Breakwell, J. A.
core +1 more source
Wrinkling of a bilayer membrane [PDF]
, 2006 The buckling of elastic bodies is a common phenomenon in the mechanics of solids. Wrinkling of membranes can often be interpreted as buckling under constraints that prohibit large amplitude deformation.
A. Concha +8 more
core +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source