Results 61 to 70 of about 677,770 (306)

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

open access: yeseLife, 2018
Macromolecular complexes that exhibit continuous forms of structural flexibility pose a challenge for many existing tools in cryo-EM single-particle analysis. We describe a new tool, called multi-body refinement, which models flexible complexes as a user-
Takanori Nakane   +3 more
doaj   +1 more source

Combining active structural damping and active suspension control in flexible bodied railway vehicles [PDF]

open access: yes, 2016
There is a desire to design lightweight railway vehicle bodies for future high speed trains. Previously, suppression of structural vibration of the flexible lightweight vehicle body was attempted via use of active suspensions (conventional actuators) or ...
Goodall, Roger   +2 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

MBD analysis of flexible multibody system with mass loss

open access: yesNihon Kikai Gakkai ronbunshu, 2016
In this paper, we propose a formulation method for flexible multi-body systems with mass loss. The method derives the equation of motion using the velocity transformation method, in consideration of the shift of center-of-mass.
Kanjuro MAKIHARA   +2 more
doaj   +1 more source

Obstrucción por cuerpos extraños localizados en esófago : terapéutica endoscópica. Tres casos clínicos [PDF]

open access: yes, 1989
Se presentan tres casos clínicos de obstrucción esofágica por cuerpos extraños en posición precardial que son extraídos por técnica endoscópica con fibroencloscopio flexible.Three clinical cases of oesophagus obstruction due to foreign bodies in ...
Aguado Sebastián, F.   +5 more
core  

Hovering of a passive body in an oscillating airflow

open access: yes, 2006
International audienceSmall flexible bodies are observed to hover in an oscillating air column. The air is driven by a large speaker at frequencies in the range 10–65 Hz at amplitudes 1–5 cm. The bodies are made of stiffened tissue paper, bent to form an
Childress, Stephen   +2 more
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Application of composite flexible body modeling method in the analysis of friction hoist dynamic stress response

open access: yesMathematical and Computer Modelling of Dynamical Systems
In order to obtain the dynamic stress response of the drum and main shaft of a friction hoist under dynamic loads, a dynamic stress calculation model for the friction hoist was constructed based on the flexible multibody modelling method.
Kai Xu, Ying Xiao, Yi Liu
doaj   +1 more source

Energy indicators of working bodies for tillage of steam fields in summer [PDF]

open access: yesBIO Web of Conferences
Currently, one of the most important stages in obtaining high yields of the main crops is tillage of steam fields in summer. The article considers various variants of working bodies for tillage of steam fields to establish the energy indicators of the ...
Kambulov Sergey   +4 more
doaj   +1 more source

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