Results 111 to 120 of about 36,842 (272)

Parallelized TCSPC for dynamic intravital fluorescence lifetime imaging: quantifying neuronal dysfunction in neuroinflammation.

PLoS ONE, 2013
Two-photon laser-scanning microscopy has revolutionized our view on vital processes by revealing motility and interaction patterns of various cell subsets in hardly accessible organs (e.g. brain) in living animals.
Jan Leo Rinnenthal, Christian Börnchen, Helena Radbruch, Volker Andresen, Agata Mossakowski, Volker Siffrin, Thomas Seelemann, Heinrich Spiecker, Ingrid Moll, Josephine Herz, Anja E Hauser, Frauke Zipp, Martin J Behne, Raluca Niesner   +13 more
doaj   +1 more source

Investigation of Mitochondrial Metabolic Response to Doxorubicin in Prostate Cancer Cells: An NADH, FAD and Tryptophan FLIM Assay

Scientific Reports, 2017
Prostate cancer (PCa) is one of the leading cancers in men in the USA. Lack of experimental tools that predict therapy response is one of the limitations of current therapeutic regimens.
S. R. Alam, Horst Wallrabe, Z. Svindrych, A. Chaudhary, Kathryn G. Christopher, D. Chandra, A. Periasamy   +6 more
semanticscholar   +1 more source

Quantitative assessment of masticatory muscles based on skull muscle attachment areas in Carnivora

The Anatomical Record, EarlyView.
Abstract Masticatory muscles are composed of the temporalis, masseter, and pterygoid muscles in mammals. Each muscle has a different origin on the skull and insertion on the mandible; thus, all masticatory muscles contract in different directions. Collecting in vivo data and directly measuring the masticatory muscles anatomically in various Carnivora ...
Kai Ito, Mugino O. Kubo, Ryo Kodera, Sei‐ichiro Takeda, Hideki Endo   +4 more
wiley   +1 more source

Fluorescence Lifetime Imaging Microscopy (FLIM) Data Analysis with TIMP [PDF]

Fluorescence Lifetime Imaging Microscopy (FLIM) allows fluorescence lifetime images of biological objects to be collected at 250 nm spatial resolution and at (sub-)nanosecond temporal resolution.
Antonie J. W. G. Visser, Ivo H. M. van Stokkum, Jan Willem Borst, Katharine M. Mullen, Sergey Laptenok, Vladimir V. Apanasovich   +5 more
core   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

FRET‐Based Investigation of the Dynamics of Peptide‐Folded Single Chain Nanoparticles Inside Cancer Cells

Macromolecular Rapid Communications, EarlyView.
Little is known about the cellular uptake of single chain nanoparticles that are cross‐linked with dynamic bonds. Using Förster resonance energy transfer and fluorescence lifetime imaging microscopy (FRET‐FLIM) the dynamic nature of the bonds is seen, in which the interaction between two peptides, disassemble quickly, relatively.
Shegufta Farazi, Radhika Raveendran, Alexander MacMillan, Jarrod T. Hillyer, Robert Chapman, Martina H. Stenzel   +5 more
wiley   +1 more source

Experimental detection of steerability in Bell local states with two measurement settings

, 2017
Steering, a quantum property stronger than entanglement but weaker than non-locality in the quantum correlation hierarchy, is a key resource for one-sided device-independent quantum key distribution applications, in which only one of the communicating ...
Diamanti, Eleni, Kaplan, Marc, Orieux, Adeline, Pramanik, Tanumoy, Venuti, Vivien, Zaquine, Isabelle   +5 more
core   +1 more source

Direct Synthesis of Exfoliated Carbon Nitride Mediated by Sodiated Cellulose Nanocrystals for Photocatalytic and Adsorbent Applications

Small, EarlyView.
Few atomic‐layer‐thick carbon nitride nanosheets (CNNS) were synthesized using an in situ exfoliation technique. The directly exfoliated CNNS exhibited a wider electronic bandgap along with a fourfold increase in specific surface area and tenfold increase in pore volume.
Narendra Chaulagain, Kazi M. Alam, Ehsan Shahini, John C. Garcia, Md Masud Rana, Riley W. Hooper, Diganta Sarkar, Damini Vrushabendrakumar, Harshitha Rajashekhar, Navneet Kumar, Alkiviathes Meldrum, Vladimir K. Michaelis, Tian Tang, Karthik Shankar   +13 more
wiley   +1 more source

Overcoming photon and spatiotemporal sparsity in fluorescence lifetime imaging with SparseFLIM

Communications Biology
Fluorescence lifetime imaging microscopy (FLIM) provides quantitative readouts of biochemical microenvironments, holding great promise for biomedical imaging.
Binglin Shen, Yuan Lu, Fangyin Guo, Fangrui Lin, Rui Hu, Feng Rao, Junle Qu, Liwei Liu   +7 more
doaj   +1 more source