Results 91 to 100 of about 36,842 (272)

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

Angular fluctuations in the CXB: Is Fe 6.4 keV line tomography of the large-scale structure feasible?

, 2012
AGN are known to account for a major portion, if not all, of the cosmic X-ray background radiation. The dominant sharp spectral feature in their spectra is the 6.4 keV fluorescent line of iron, which may contribute to as much as ~ 5-10 % of the CXB ...
Aird, Alexander, Allevato, Bambynek, Basko, Brandt, Carilli, Chaudhary, Coil, Comastri, Cooray, Dijkstra, Fabian, Furlanetto, G. Hütsi, Gandhi, Giacconi, Giacconi, Gilli, Gilli, Gilli, Gong, Huterer, Iwasawa, Jungman, Knox, Krumpe, La Franca, Lehmer, Lidz, M. Gilfanov, McQuinn, Miyaji, Miyaji, Murray, Padmanabhan, Pritchard, R. Sunyaev, Revnivtsev, Righi, Sheth, Sheth, Shu, Shu, Starikova, Tegmark, Treister, Ueda, Worrall, Xue   +49 more
core   +1 more source

FLiMS: Fast Lightweight Merge Sorter

2018 International Conference on Field-Programmable Technology (FPT), 2018
We have developed a highly-efficient and simple parallel hardware design for merging two sorted lists residing in banked (or multi-ported) memory. The FPGA implementation uses half the hardware resources required for implementing the current state-of-the-art architecture.
Papaphilippou, P, Brooks, C, Luk, W
openaire   +2 more sources

Segmented cell analyses to measure redox states of autofluorescent NAD(P)H, FAD & Trp in cancer cells by FLIM

Scientific Reports, 2018
Multiphoton FLIM microscopy offers many opportunities to investigate processes in live cells, tissue and animal model systems. For redox measurements, FLIM data is mostly published by cell mean values and intensity-based redox ratios. Our method is based
Horst Wallrabe, Z. Svindrych, S. R. Alam, K. Siller, Tianxiong Wang, David F. Kashatus, Song Hu, A. Periasamy   +7 more
semanticscholar   +1 more source

Alcohol‐Adduct Mediated Precursor Stabilization Strategies for Conformal SnO2 Layers in Highly Efficient and Stable Perovskite Solar Modules

Advanced Energy Materials, EarlyView.
An alcohol‐adduct‐mediated strategy is employed to stabilize tin isopropoxide for the formation of a homogeneous double electron transport layer (ETL) incorporating SnO2 nanoparticles (NPs). This double‐ETL exhibits improved optical and charge‐transport properties due to reduced defect density and better energy level alignment, resulting in high ...
You‐Hyun Seo, Eun Young Park, Chan Su Moon, Dong Gyu Lee, Junho Park, Fabian Rotermund, Gill Sang Han, Tae Kyung Lee, Nam Joong Jeon, Bong Joo Kang, Young Yun Kim   +10 more
wiley   +1 more source

Regulatory assembly of the vacuolar proton pump VOV1-ATPase in yeast cells by FLIM-FRET

, 2010
We investigate the reversible disassembly of VOV1-ATPase in life yeast cells by time resolved confocal FRET imaging. VOV1-ATPase in the vacuolar membrane pumps protons from the cytosol into the vacuole. VOV1-ATPase is a rotary biological nanomotor driven
Batisse, Claire, Boersch, Michael, Boettcher, Bettina, Ernst, Stefan, Zarrabi, Nawid   +4 more
core   +1 more source

MOA-2011-BLG-293Lb: A test of pure survey microlensing planet detections [PDF]

, 2012
Because of the development of large-format, wide-field cameras, microlensing surveys are now able to monitor millions of stars with sufficient cadence to detect planets.
A. Fukui, A. Gal-Yam, A. Gould, A. Udalski, Albrow, Albrow, Alcock, An, B. S. Gaudi, Bennett, Bennett, Bonfils, Boss, C. H. Ling, C. Han, C. Henderson, C. S. Botzler, C.-U. Lee, Choi, Claret, D. Higgins, D. J. Sullivan, D. L. DePoy, D. Maoz, D. McGregor, D. Moorhouse, D. P. Bennett, D. Suzuki, Dong, Dong, Dong, E. Gorbikov, E. Ofek, F. Abe, F. Jablonski, G. Christie, G. Pietrzyński, G. Thornley, Gaudi, Gaudi, Gould, Gould, Gould, Gould, Gould, Griest, H. Ngan, Han, I. A. Bond, I. Finkelman, I. Manulis, I. Soszyński, I.-G. Shin, Ida, J. A. Muñoz, J. C. Yee, J. Drummond, J. McCormick, J. Skowron, J.-R. Koo, J.-Y. Choi, Janczak, Johnson, K. Furusawa, K. Masuda, K. Ohmori, K. Ohnishi, K. Suzuki, K. Ulaczyk, K. Wada, L. A. Almeida, L. A. G. Monard, Laughlin, M. Bos, M. Freeman, M. K. Szymański, M. Kubiak, N. J. Rattenbury, N. Miyake, P. Chote, P. J. Tristram, P. Pietrukowicz, Pejcha, R. Poleski, R. Santallo, R. W. Pogge, S. Kaspi, S. Kobara, S. Kozłowski, S. Takino, S.-Y. Park, Subo Dong, Sumi, T. Natusch, T. Sumi, T.-G. Tan, To. Saito, Udalski, Udalski, V. Batista, W. Allen, W. L. Sweatman, Wozniak, Y. Itow, Y. Matsubara, Y. Muraki, Y. Shvartzvald, Yee, Yoo, Ł. Wyrzykowski   +109 more
core   +3 more sources

A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses

bioRxiv, 2019
Stem cells and the niche in which they reside feature a complex microenvironment with tightly regulated homeostasis, cell-cell interactions and dynamic regulation of metabolism.
I. Okkelman, N. Neto, D. Papkovsky, M. Monaghan, R. Dmitriev   +4 more
semanticscholar   +1 more source

Macrophage Phenotype Detection Methodology on Textured Surfaces via Nuclear Morphology Using Machine Learning

Advanced Intelligent Discovery, EarlyView.
A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi, Kateryna Andriienkova, Tetyana Goldanova, Ezgi Antmen, Thibaut Soubrie, Nihal Engin Vrana   +5 more
wiley   +1 more source

Quantitative Analysis of Acquisition Speed of High-Precision FLIM Technologies via Simulation and Modeling

Photonics
In practical applications such as cancer diagnosis and industrial detection, there is a critical demand for fast fluorescence lifetime imaging (Fast-FLIM).
Jinzheng Lu, Ling Miao, Jiaxing Wen, Qiang Li, Jingwei Chen, Qiang Yang, Xing Zhang, Jin Li, Yuchi Wu, Yue Yang, Sixin Wu, Wenbo Mo, Qiang Xiang   +12 more
doaj   +1 more source