Results 71 to 80 of about 36,842 (272)

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Probing the Cosmic X-ray and MeV Gamma-ray Background Radiation through the Anisotropy

, 2013
While the cosmic soft X-ray background is very likely to originate from individual Seyfert galaxies, the origin of the cosmic hard X-ray and MeV gamma-ray background is not fully understood. It is expected that Seyferts including Compton thick population
Inoue, Yoshiyuki, Madejski, Grzegorz M., Murase, Kohta, Uchiyama, Yasunobu   +3 more
core   +2 more sources

Development of fluorescence lifetime biosensors for ATP, cAMP, citrate, and glucose using the mTurquoise2-based platform

Cell Reports: Methods
Summary: Single-fluorescent protein (FP)-based FLIM (fluorescence lifetime imaging microscopy) biosensors can visualize intracellular processes quantitatively. They require a single wavelength for detection, which facilitates multi-color imaging. However,
Chongxia Zhong, Satoshi Arai, Yasushi Okada   +2 more
doaj   +1 more source

Machine Learning Methods for Fluorescence Lifetime Imaging (FLIM) Based Label-Free Detection of Microglia

Frontiers in Neuroscience, 2020
Automated computational analysis techniques utilizing machine learning have been demonstrated to be able to extract more data from different imaging modalities compared to traditional analysis techniques.
M. A. Sagar, Kevin P. Cheng, Jonathan N. Ouellette, Justin C. Williams, J. Watters, K. Eliceiri   +5 more
semanticscholar   +1 more source

Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]

, 2019
Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana, Conway, Robert Max, Gratton, Enrico, Macmillan, Alexander, Madigan, Michele C, Sitiwin, Ephrem, Whan, Renee   +6 more
core  

Detection of frequency deviations for monitoring of power systems [PDF]

, 2019
​© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new ...
Dobrowolski, Jean, Korba, Petr, Obusevs, Artjoms, Segundo Sevilla, Felix Rafael   +3 more
core   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Quantitative Imaging of Genetically Encoded Fluorescence Lifetime Biosensors

Biosensors, 2023
Genetically encoded fluorescence lifetime biosensors have emerged as powerful tools for quantitative imaging, enabling precise measurement of cellular metabolites, molecular interactions, and dynamic cellular processes.
Cong Quang Vu, Satoshi Arai
doaj   +1 more source

Probing subtle fluorescence dynamics in cellular proteins by streak camera based Fluorescence Lifetime Imaging Microscopy

, 2003
We report the cell biological applications of a recently developed multiphoton fluorescence lifetime imaging microscopy system using a streak camera (StreakFLIM).
Biener, Eva, Heckel, Robert, Herman, Brian, Krishnan, R. V., Zhang, Jian-Hua   +4 more
core   +1 more source

Structure of HrcQ(B)-C, a conserved component of the bacterial type III secretion systems [PDF]

, 2003
Type III secretion systems enable plant and animal bacterial pathogens to deliver virulence proteins into the cytosol of eukaryotic host cells, causing a broad spectrum of diseases including bacteremia, septicemia, typhoid fever, and bubonic plague in ...
A. P. Tampakaki, Alfano, Anderson, Br  nger, Charkowski, Collmer, Fadouloglou, Francis, Galan, Garcia de la Torre, Gouet, Hueck, J. M. Hadden, Jin, Kubori, Landgraf, Lloyd, Luo, M. Kokkinidis, M. N. Bastaki, Mathews, McGuffin, Murshudov, N. J. Panopoulos, N. M. Glykos, Rossier, S. E. Phillips, Stebbins, Tamano, Tang, Terwilliger, Terwilliger, V. E. Fadouloglou, Zhao   +33 more
core   +2 more sources