Results 91 to 100 of about 6,623,538 (310)

Flow grammars — a flow analysis methodology [PDF]

open access: yes, 1994
Flow grammars provide a new mechanism for modeling control flow in flow analyzers and code optimizers. Existing methods for representing control flow are inadequate in terms of both their generality and their accuracy. Flow grammars overcome these deficiencies and are well-suited to the specification and solution of data flow analysis problems.
James S. Uhl, R. Nigel Horspool
openaire   +2 more sources

Numerical Simulation of Flow Field Formed in Water Pump-Sump [PDF]

open access: yes, 2008
Two fundamental types of flow problems besetting water intakes are swirling flow problems in the pump sump and sediment problems at entrance or within intakes.
BOIS, Gérard   +2 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Simulating the urban canopy’s impact on wind-driven natural ventilation

open access: yesFlow
The urban canopy affects wind in complex ways, making it challenging to predict wind-driven natural ventilation and cooling in buildings. Using large eddy simulations of coupled outdoor and indoor airflow, we study how the surrounding urban canopy and ...
Nicholas Bachand   +2 more
doaj   +1 more source

A curvature flow unifying symplectic curvature flow and pluriclosed flow [PDF]

open access: yesPacific Journal of Mathematics, 2015
Corrected minor errors and updated references.
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Mixing and ventilation in a living laboratory due to fast and slow response modes

open access: yesFlow
We present and analyse observational data from a highly instrumented classroom computer laboratory and develop a multi-zone model to describe its mechanical ventilation and mixing regime.
Costanza Rodda   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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