Results 71 to 80 of about 6,124,378 (340)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A novel multipath-transmission supported software defined wireless network architecture [PDF]

open access: yes, 2017
The inflexible management and operation of today\u27s wireless access networks cannot meet the increasingly growing specific requirements, such as high mobility and throughput, service differentiation, and high-level programmability.
Jin, Wenqiang   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Control Flow Analysis for SF Combinator Calculus

open access: yes, 2015
Programs that transform other programs often require access to the internal structure of the program to be transformed. This is at odds with the usual extensional view of functional programming, as embodied by the lambda calculus and SK combinator ...
Lester, Martin
core   +4 more sources

Operating Power Grids with Few Flow Control Buses

open access: yes, 2015
Future power grids will offer enhanced controllability due to the increased availability of power flow control units (FACTS). As the installation of control units in the grid is an expensive investment, we are interested in using few controllers to ...
Leibfried, Thomas   +7 more
core   +1 more source

Multi-Gated Perimeter Flow Control of Transport Networks [PDF]

open access: yes, 2017
This paper develops a control scheme for the multi-gated perimeter traffic flow control problem of urban road networks. The proposed scheme determines optimally distributed input flows (or feasible entrance link green times) for a number of gates located
Ampountolas, Konstantinos   +1 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Effect of Pitch Angle on Structural and Aerodynamic Characteristics of Vertical-Axis Wind Turbines (VAWTs) Using Leading-Edge Protuberance Blades

open access: yesEnergies
An experimental investigation was carried out to understand the effects of LEP (leading-edge protuberance) blades on the structural characteristics of VAWTs. A series of experiments were performed on VAWTs with straight and LEP blades for a wide range of
Karthikvel Elangovan, S. Nadaraja Pillai
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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