Results 81 to 90 of about 20,769,954 (368)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Effect of Pitch Angle on Structural and Aerodynamic Characteristics of Vertical-Axis Wind Turbines (VAWTs) Using Leading-Edge Protuberance Blades

open access: yesEnergies
An experimental investigation was carried out to understand the effects of LEP (leading-edge protuberance) blades on the structural characteristics of VAWTs. A series of experiments were performed on VAWTs with straight and LEP blades for a wide range of
Karthikvel Elangovan, S. Nadaraja Pillai
doaj   +1 more source

Adjoint-based machine learning for active flow control [PDF]

open access: yesarXiv, 2023
We develop neural-network active flow controllers using a deep learning PDE augmentation method (DPM). The sensitivities for optimization are computed using adjoints of the governing equations without restriction on the terms that may appear in the objective function.
arxiv  

Thermal Metamaterials for Heat Flow Control in Electronics

open access: yes, 2017
Rapid advancement of modern electronics has pushed the limits of traditional thermal management techniques. Novel approaches to the manipulation of the flow of heat in electronic systems have potential to open new design spaces.
E. Dede   +3 more
semanticscholar   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Load-Flow Solvability under Security Constraints in DC Distribution Networks [PDF]

open access: yesarXiv, 2022
We present sufficient conditions for the load-flow solvability under security constraints in DC distribution networks. In addition, we show that a load-flow solution that fulfills security constraints can be obtained via a convex optimization.
arxiv  

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

A Localized Method for the Multi-commodity Flow Problem [PDF]

open access: yesarXiv, 2021
This paper presents a local-control approach to address the multicommodity flow problem. The method involves relaxing both capacity constraints and flow conservation constraints. If the flow exceeds the capacity on an edge, the edge would incur a congestion cost.
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Operating Power Grids with Few Flow Control Buses [PDF]

open access: yesarXiv, 2015
Future power grids will offer enhanced controllability due to the increased availability of power flow control units (FACTS). As the installation of control units in the grid is an expensive investment, we are interested in using few controllers to achieve high controllability.
arxiv  

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