Results 91 to 100 of about 5,219,938 (357)
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry
bioRxiv, 2018 New techniques for single-cell analysis have led to insights into hematopoiesis and the immune system, but the ability of these techniques to cross-validate and reproducibly identify the biological variation in diverse human samples is currently unproven.
K. Oetjen +8 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Simple Detection of Unstained Live Senescent Cells with Imaging Flow Cytometry [PDF]
, 2022 Marco Malavolta +16 more
openalex +1 more source
Clinical & Translational Immunology, 2020 The tumor microenvironment is an integral player in cancer initiation, tumor progression, response and resistance to anti‐cancer therapy. Understanding the complex interactions of tumor immune architecture (referred to as ‘immune contexture’) has ...
Reshma Shakya +3 more
doaj +1 more source
How Clinical Flow Cytometry Rebooted Sepsis Immunology
Cytometry Part A, 2019 On May 2017, the World Health Organization (WHO) recognized sepsis as a global health priority by adopting a resolution to improve the prevention, diagnosis, and management of this deadly disease.
G. Monneret +4 more
semanticscholar +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes
Cells, 2014 Herpes simplex virus type 1 (HSV-1) is a significant human pathogen that infects a large portion of the human population. Cells deploy a variety of defenses to limit the extent to which the virus can replicate.
Miles C. Smith +4 more
doaj +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
FEBS Open Bio, EarlyView.The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Spectral flow cytometry—Quo vadimus?
Cytometry Part A, 2019 FOR 40 years, flow cytometry has been dominated by polychromatic flow cytometry. Despite the fact that Fulwyler’s instrument (1) was based on Coulter volume, fluorescence became the dominant technology within a very few years.
J. Paul Robinson
semanticscholar +1 more source