Results 91 to 100 of about 5,519,742 (398)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Human Blood Cell Sensing with Platinum Black Electroplated Impedance Sensor [PDF]

, 2007
AC impedance sensing is an important method for biological cell analysis in flow cytometry. For micro impedance cell sensors, downsizing electrodes increases the double layer impedance of the metal-electrolyte interface, thus leaves no sensing zone in ...
Nandra, Mandheerej S., Tai, Yu-Chong, Zheng, Siyang   +2 more
core   +1 more source

High-throughput label-free molecular fingerprinting flow cytometry

Science Advances, 2019
High-throughput Raman flow cytometry is developed to rapidly probe molecular fingerprints of numerous cells without labels. Flow cytometry is an indispensable tool in biology for counting and analyzing single cells in large heterogeneous populations ...
K. Hiramatsu, T. Ideguchi, Yusuke Yonamine, Sangwook Lee, Yizhi Luo, K. Hashimoto, Takuro Ito, Misa Hase, Jee-Woong Park, Y. Kasai, S. Sakuma, T. Hayakawa, F. Arai, Yuta Hoshino, K. Goda   +14 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Differential effects on membrane permeability and viability of human keratinocyte cells undergoing very low intensity megasonic fields [PDF]

, 2017
Among different therapeutic applications of Ultrasound (US), transient membrane sonoporation (SP) - a temporary, non-lethal porosity, mechanically induced in cell membranes through US exposure - represents a compelling opportunity towards an efficient ...
Bedini, A, Bordi, F., Brasili, F, Cerroni, B, Domenici, F, Giantulli, S, Giliberti, 4, Mattei, M, Morrone, S, Palomba, R, Paradossi, G, Silvestri, I   +11 more
core   +1 more source

Impact of high-sensitivity flow cytometry on peri-transplant minimal residual disease kinetics in acute leukemia

Scientific Reports
Minimal residual disease (MRD) detected before hematopoietic cell transplantation (HCT) is associated with adverse outcomes in patients with high-risk acute leukemia.
Ana Paula de Azambuja, Miriam Perlingeiro Beltrame, Mariester Malvezzi, Yara Carolina Schluga, Julie Lillian Pimentel Justus, Alberto Cardoso Martins Lima, Vaneuza Araujo Moreira Funke, Carmem Bonfim, Ricardo Pasquini   +8 more
doaj   +1 more source

Flow Cytometry as the Tool to Define Peripheral Blood Leukocyte Signatures in Acute EBV Infection

Cells
Primary Epstein–Barr virus (EBV) infection which can manifest as infectious mononucleosis (IM) is commonly acquired during childhood. EBV primarily invades B cells leading to a lytic reaction; the control of the infection is handled by natural killer and
Pragya Singh, Manisha Gadgeel, Batool AlQanber, Ahmad Farooqi, Süreyya Savaşan   +4 more
doaj   +1 more source

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma.

Journal of Clinical Oncology, 2019
PURPOSE Assessing measurable residual disease (MRD) has become standard with many tumors, but the clinical meaning of MRD in multiple myeloma (MM) remains uncertain, particularly when assessed by next-generation flow (NGF) cytometry.
B. Paiva, N. Puig, M. Cedena, L. Rosiñol, L. Cordón, M. Vidriales, L. Burgos, J. Flores-Montero, Luzalba Sanoja-Flores, L. López-Anglada, R. Maldonado, J. De la Cruz, N. Gutiérrez, M. Calasanz, M. Martín-Ramos, R. García-Sanz, J. Martínez-López, A. Oriol, M. Blanchard, R. Ríos, Jesús Martín, R. Martínez-Martínez, A. Sureda, M. Hernandez, J. de la Rubia, I. Krsnik, J. Moraleda, L. Palomera, J. Bargay, J. V. van Dongen, A. Órfão, M. Mateos, J. Bladé, J. San-Miguel, J. Lahuerta   +34 more
semanticscholar   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Consequences of cell-to-cell P-glycoprotein transfer on acquired multidrug resistance in breast cancer: a cell population dynamics model [PDF]

, 2010
Cancer is a proliferation disease affecting a genetically unstable cell population, in which molecular alterations can be somatically inherited by genetic, epigenetic or extragenetic transmission processes, leading to a cooperation of neoplastic cells ...
Boulangé-Lecomte, Céline, Foll, Frank Le, Magal, Pierre, Pasquier, Jennifer, Webb, Glenn   +4 more
core   +5 more sources