Results 31 to 40 of about 173,196 (125)
optimalFlow: Optimal-transport approach to flow cytometry gating and population matching [PDF]
arXiv, 2019 Data obtained from Flow Cytometry present pronounced variability due to biological and technical reasons. Biological variability is a well-known phenomenon produced by measurements on different individuals, with different characteristics such as illness, age, sex, etc.
arxiv
Cameraless High-throughput 3D Imaging Flow Cytometry [PDF]
arXiv, 2019 Increasing demand for understanding the vast heterogeneity of cellular phenotypes has driven the development of imaging flow cytometry (IFC), that combines features of flow cytometry with fluorescence and bright field microscopy. IFC combines the throughput and statistical advantage of flow cytometry with the ability to discretely measure events based ...
arxiv
The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome
Frontiers in Immunology, 2019 Sepsis remains a major challenge in translational research given its heterogeneous pathophysiology and the lack of specific therapeutics. The use of humanized mouse chimeras with transplanted human hematopoietic cells may improve the clinical relevance ...
Tomasz Skirecki +7 more
doaj +1 more source
TEAM: A Multiple Testing Algorithm on the Aggregation Tree for Flow Cytometry Analysis [PDF]
arXiv, 2019 In immunology studies, flow cytometry is a commonly used multivariate single-cell assay. One key goal in flow cytometry analysis is to pinpoint the immune cells responsive to certain stimuli. Statistically, this problem can be translated into comparing two protein expression probability density functions (PDFs) before and after the stimulus; the goal ...
arxiv
Scientific ReportsMinimal residual disease (MRD) detected before hematopoietic cell transplantation (HCT) is associated with adverse outcomes in patients with high-risk acute leukemia.
Ana Paula de Azambuja +8 more
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Flow Cytometry as the Tool to Define Peripheral Blood Leukocyte Signatures in Acute EBV Infection
CellsPrimary Epstein–Barr virus (EBV) infection which can manifest as infectious mononucleosis (IM) is commonly acquired during childhood. EBV primarily invades B cells leading to a lytic reaction; the control of the infection is handled by natural killer and
Pragya Singh +4 more
doaj +1 more source
A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes
Cells, 2014 Herpes simplex virus type 1 (HSV-1) is a significant human pathogen that infects a large portion of the human population. Cells deploy a variety of defenses to limit the extent to which the virus can replicate.
Miles C. Smith +4 more
doaj +1 more source
Clinical & Translational Immunology, 2020 The tumor microenvironment is an integral player in cancer initiation, tumor progression, response and resistance to anti‐cancer therapy. Understanding the complex interactions of tumor immune architecture (referred to as ‘immune contexture’) has ...
Reshma Shakya +3 more
doaj +1 more source
Corrected score methods for estimating Bayesian networks with error-prone nodes [PDF]
arXiv, 2020 Motivated by inferring cellular signaling networks using noisy flow cytometry data, we develop procedures to draw inference for Bayesian networks based on error-prone data. Two methods for inferring causal relationships between nodes in a network are proposed based on penalized estimation methods that account for measurement error and encourage ...
arxiv
Frontiers in Pharmacology, 2020 Wistar rats were whole body irradiated with a single dose of 2 Gy post administration with 10 or 100 mg/kg of resveratrol (RSV) intraperitoneally for 30 days. Rats’ livers were dissected and processed to analyze immune response profiles of Th1, Th2, Th9,
Ayman Khalil +4 more
doaj +1 more source