Results 41 to 50 of about 796,572 (314)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Seven-year study of viability and absolute counts in cord blood units by flow cytometry in Greece

International Journal of Hematology-Oncology and Stem Cell Research, 2015
#No Abstract#
Vasiliki E-Kalodimou, Irene Mitrou, Antonio Vlachousis   +2 more
doaj  

Unravelling Plasma Extracellular Vesicle Diversity With Optimised Spectral Flow Cytometry

Journal of Extracellular Biology
Extracellular vesicles (EVs) are crucial for intercellular communication and are found in various biological fluids. The identification and immunophenotyping of such small particles continue to pose significant challenges.
Daniela Boselli, Francesca Clemente, Simona Di Terlizzi, Christina Pagiatakis, Laura Papa, Genny Del Zotto, Chiara Villa, Giuseppe Alvise Ramirez, Norma Maugeri, Angelo A. Manfredi, Achille Anselmo   +10 more
doaj   +1 more source

Analyzing the involvement of diverse cell death-related genes in diffuse large B-cell lymphoma using bioinformatics techniques

Heliyon
Diffuse large B-cell lymphoma (DLBCL) stands as the most prevalent subtype of non-Hodgkin's lymphoma and exhibits significant heterogeneity. Various forms of programmed cell death (PCD) have been established to have close associations with tumor onset ...
Heyuan Feng, Xiyuan Zhang, Jian Kang
doaj   +1 more source

Evaluation of CD38 expression in Sudanese patients with chronic lymphocytic leukemia

BMC Research Notes, 2018
Objective The objective of this study was to evaluate the cluster of differentiation-38 (CD38) expression in Sudanese patients with chronic lymphocytic leukemia (CLL) and to determine its association with clinical and laboratory characteristics of the ...
Enaam Abdelrhman Abdelgader, Nada Hassan Eltayeb, Tasniem Ahmed Eltahir, Osama Ali Altayeb, Eman Abbass Fadul, Eldirdiri M. Abdel Rahman, Tarig H. Merghani   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Bi-lineage acute leukemia; a case with B-lymphoblasts and myeloid blasts [PDF]

Journal of Preventive Epidemiology, 2019
Mixed phenotypic acute leukemia (MPAL) is classified under acute leukemia of ambiguous lineage. Most reported cases of acute ambiguous leukemia belong to bi-phenotypic leukemia. However, bi-lineage leukemia is rare.
Esmaeil Shahabi Satlsar, Farahnaz Ghahremanfard, Anahid Nabavi, Mohammad Moslehabadi Farahani   +3 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Flow Cytometry for Rapid Determination of Number of Microbial Cells Grown on Fish

, 2002
Application of the flow cytometry (FCM) technique for rapid determination of the total number of microbial cells grown on yellow-fin horse mackerel was described. An ultrasonic treatment was used to remove the cells on seafood samples of yellow-fin horse,
任, 恵峰, Ren, Huifeng, Hayashi, Tetsuhito, 遠藤, 英明, ハヤシ, テツヒト, 林, 哲仁, エンドウ, ヒデアキ, Nakamura, Junichi, Endo, Hideaki, ニン, ケイホウ   +9 more
core   +1 more source

A rapid and reliable method of counting neurons and other cells in brain tissue: a comparison of flow cytometry and manual counting methods

Frontiers in Neuroanatomy, 2010
It is of critical importance to understand the numbers and distributions of neurons and non-neurons in the cerebral cortex because cell numbers are reduced with normal aging and by diseases of the CNS.
Christine E Collins, Nicole A Young, David K Flaherty, David C Airey, Jon H Kaas   +4 more
doaj   +1 more source